rigidity

Table 19: Incidence of EPS Compared to Placebo in the Adjunctive Therapy Bipolar Depression Studies LATUDA Placebo 20to 120 mg/day (N=334) (N=360) Adverse Event Term (%) (%) All EPS events 13 24 All EPS events, excluding 9 14 Akathisia/ Restlessness Akathisia 5 11 Dystonia * <1 1 Parkinsonism ** 8 13 Restlessness <1 4 Note: Figures rounded to the nearest integer * Dystonia includes adverse event terms: dystonia, oculogyric crisis, oromandibular dystonia, tongue spasm, torticollis, and trismus ** Parkinsonism includes adverse event terms: bradykinesia, cogwheel rigidity, drooling, extrapyramidal disorder, glabellar reflex abnormal, hypokinesia, muscle rigidity, parkinsonism, psychomotor retardation, and tremor

However, cogwheel rigidity remained minimally improved and respiration was irregular.

Patients with PD also may have cogwheel rigidity, a masked face, and trouble rising from a chair.

Patients with PD have other associated symptoms and signs, such as cogwheel rigidity, a masked face, and trouble rising from a chair.

On admission, he was febrile, had altered mental status, osciliopsia, and cogwheel rigidity.