The Electrophysiological Patch Clamp technique was used to characterize ERG channels in cochlear nucleus tissue.
It should be emphasized that the data from cochlear nucleus was obtained using aCSF that does not contain Ca as in the studies conducted by Sacco et al.
Turner et al., "Plasticity at glycinergic synapses in dorsal cochlear nucleus of rats with behavioral evidence of tinnitus," Neuroscience, vol.
Canlon, "Modulating calbindin and parvalbumin immunoreactivity in the cochlear nucleus by moderate noise exposure in mice.: a quantitative study on the dorsal and posteroventral cochlear nucleus," Brain Research, vol.
Yin, "Enhancement of neural synchronization in the anteroventral cochlear nucleus
Stimulus coding in the cochlear nucleus
. Trans Am Otol Soc.
The Cochlear Nucleus
24 Contour Advance features an enhanced Contour Electrode engineered to help preserve and protect the delicate structures of the cochlea during surgery and in the years following surgery.
Research is still being conducted on the effects of loud noises on a part of the brain referred to as the dorsal cochlear nucleus
, the relay that carries signals from nerve cells in the ear to the parts of the brain that decode and make sense of sounds.
In human subjects who had postlingual onset of bilateral profound hearing loss, changes in cell size have been observed in the cochlear nucleus
(anterior division), superior olivary nucleus (medial portion), and inferior colliculus (IC) .
Cochlear implants are used in people who are deaf or have severe hearing loss caused by the loss of cochlear hair cells; auditory brainstem implants provide stimulation of the cochlear nucleus
in people whose auditory nerves do not function.
High-intensity noise also can alter the normal neural coding processes of auditory signals in individual nuclei along the auditory pathway, including the cochlear nucleus
, inferior colliculus (IC), and auditory cortex [14, 16-20].
Peaks III to V (up to seven peaks were observed in some studies) represent the responses from the cochlear nucleus
and other brainstem nuclei in higher level.
Pathologically, the volume and size of the neurons of cochlear nucleus
in deaf animal models are decreased depending on the onset and duration hearing loss [20,21].