The complex immunology of human coccidioidomycosis
. Ann NY Acad Sci 2007;1111:245-258.
(2) Systemic spread of coccidioidomycosis
is usually hematogenous and can involve bones, skin, soft tissues and, less commonly, other solid organs such as the liver or kidneys.
is caused by breathing in spores of the fungus Coccidioides immitis.
Canine Systemic Coccidioidomycosis
: Radiologic and Pathologic Study of One Case
For example, dust suppression during construction, including continuous soil-wetting and proper covering, could decrease the risk for coccidioidomycosis
among outdoor workers (23).
Amplyx had previously received QIDP designation as well as orphan drug designation from the FDA for APX001 for the treatment of invasive candidiasis, invasive aspergillosis, and coccidioidomycosis
is caused by a soil-inhabiting dimorphic spore-forming fungus Coccidioides immitis that is endemic in the southwestern region of the United States, Mexico, and parts of South America.
was first discovered in Argentina in 1892 by a medical student with the observation of several patients developing dermatologic lesions throughout the body.
Diagnosing intra-abdominal sarcoidosis is particularly challenging, as the lesions mimic neoplastic processes (e.g., lymphoma, carcinoma, or metastases) or necrotizing granulomatous infections (e.g., coccidioidomycosis
The product has received orphan drug designation for four indications: the treatment of invasive candidiasis, invasive aspergillosis, coccidioidomycosis
, and rare mold infections caused by Scedosporium spp, Fusarium spp, and Mucorales fungi.
Let's take a step back: In July 2013, the FDA strengthened its warnings and withdrew FDA indications for ketoconazole, specifically stating that its use for Candida and dermatophyte infections is no longer indicated and that it should only be considered in fungal infections, such as blastomycosis, coccidioidomycosis
, histoplasmosis, chromomycosis, and paracoccidioidomycosis, when other antifungals are not available.
was first described as a disease in an Argentinean soldier in 1892.
The differential diagnosis includes tuberculosis, cavitary histoplasmosis and coccidioidomycosis
, and neoplasias (1)(2)(9).