cobalamin

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Synonyms for cobalamin

References in periodicals archive ?
Ghosh, "Inhibition of nitric oxide synthase by cobalamins and cobinamides," Free Radical Biology and Medicine, vol.
The cobalamin (Cbl) cofactor of MS, its Cbl[I] form, directly participates in the transfer reaction by abstracting a folate-derived methyl group, temporarily creating methylcobalamin (MeCbl), and then transferring the methyl group to HCY [1].
Antibodies to intrinsic factor (AIFA), which block the binding of cobalamin to intrinsic factor, have been reported in 31-76% of patients with pernicious anemia.
Cobalamins. The coenzymes, 57-deoxyadenosylcobalamin, and methylcobalamin; Vitamin [B.sub.12]a, cyanocobalamin, and hydroxocobalamin (CAS 78091-12-0) were purchased from Sigma-Aldrich (UK).
In these circumstances, it is possible that the NO might diminish the enzyme cofactor abilities of cobalamins and produce a functional vitamin [B.sub.12] deficiency state.
A new method has been developed to measure cobalamins. It uses one of two separation techniques--capillary electrophoresis and micro-high-performance liquid chromatography--combined with a detection technique called inductively coupled plasma mass spectrometry.
The newer technique for quantifying cobalamins uses one of two separation methods.
Untreated vitamin [B.sub.12] deficiency is a prevalent and serious medical condition most often affecting elderly patients.[3] Cobalamin deficiency can have protean morbid effects on health.
Little is known about the relationship between cobalamin deficiency and mental impairment in elderly people, but cobalamin deficiency may be an important cause of mental disturbances.
Based on analyses in cobalamin-deficient patients before and after therapy, Morkbak and colleagues (1) confirm our finding that cobalamin concentrations correlate with haptocorrin (HC; transcobalamin I) (2) but propose that HC concentrations are regulated by cobalamin status rather than being genetically deter mined, which they mistake as my view.
[4] Nonstandard abbreviafions: HC, haptocorrin; TC, transcobalamin; holoHC, haptocorrin saturated with cobalamins; MMA, methylmalonic acid; and IUGR, intrauterine growth retardation.
HoIoTC calibrators (Axis-Shield) were prepared gravimetrically from a stock solution of recombinant holoTC saturated with cobalamins. The purity of the recombinant holoTC was determined by sodium dodecyl sulfate electrophoresis and spectroscopically from the ratio of the protein component and the cobalamin component.
(g) 0.7 16 M 17 AMN 1.4 17 M 23 GIF 4.1 Holo-TC, (d) Cobalamins, (e) pmol/L pmol/L Patients Sex Day 0 Increase Day 0 Increase 1 F 47 4 221 -8 2 M 72 -11 164 -20 3 M 5 1 92 9 4 F 7 1 95 2 5 F 15 0 135 5 6 F 29 2 122 22 7 F 30 -9 384 -18 8 M 18 2 184 -32 9 M 17 3 135 -17 10 M 16 3 167 -13 11 M 7 -1 96 14 12 M 13 -1 113 5 13 F 22 -1 187 -12 14 F 15 2 201 1 15 F 6 0 149 15 16 M 12 2 155 -3 17 M 6 5 122 -28 (a) A genetic diagnosis was available for 12 patients, as described in Tanner et al.