(redirected from chronic inflammatory arthritis)
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There is still a significant portion of the chronic inflammatory arthritis patient population that does not completely benefit from currently approved therapies.
Data show that adeno-associated virus (AAV) vector delivery of DNA encoding a tumor necrosis factor: immunoglobulin (IgG1) Fc (TNFR:Fc) fusion gene resulted in a significant suppression of chronic inflammatory arthritis in an animal model of disease.
We are pleased to see that AAV gene delivery of TNFR:Fc appears to have a positive impact on suppression of chronic inflammatory arthritis in animal models.
The goal of this study was to determine whether use of tgAAV-TNFR:Fc was a viable option for treating chronic inflammatory arthritis and whether local delivery could minimize systemic distribution of the TNF-a inhibitor.
Results from a study investigating the levels of BLyS in the joints and serum of inflammatory arthritis patients compared to osteoarthritis or traumatic arthritis patients to better understand the role of BLyS in chronic inflammatory arthritis were presented on Wednesday, November 14.
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