Beside this unprecedented high detection rate of common aneuploidies, some studies highlighted the usefulness of this screening strategy to detect a much broader range of chromosomal aberrations
, including triploidy, small supernumerary marker chromosomes and rare numerical and/or structural chromosomal abnormalities (5).
Louis, MO, USA) was used in the in vitro mammalian chromosomal aberrations
and in vivo mammalian micronucleus tests.
The aim of this study was to evaluate the mutagenicity of herbicide glyphosate (Roundup Full II[R]) by testing chromosomal aberrations
in fish (Prochilodus lineatus).
(%) Chromosomal 12 (9) 38 (28) abnormality cases with ultrasound diagnoses (a) Cases with 10 (4) 91 (32) malformations identified on prenatal ultrasound diagnoses Total 22 (6) 129 (31) (a) Ultrasound findings were available for 135 of the 170 chromosomal aberration
cases, with clinicopathologic correlation completed for these cases.
Effects on Chromosomal Aberration
. Dicentric chromosomes (DC), acentric fragments (AF), and chromatid breaks (ChB) were the indices used to evaluate the chromosomal aberrations
during the present study.
Enhanced ultraviolet-B (UV-B) radiation causes chromosomal aberrations
and abnormal microtubule arrays in wheat (Triticum aestivum) root cells.
Results: Mancozeb exposure (5 pg/ml) for 24h caused significant induction of chromosomal aberrations
(CAs) and micronudei (MN) formation in CHLs.
Scoring MN in interphase nuclei is technically easier and faster than scoring of chromosomal aberration
in metaphase nuclei .
After in vitro irradiation with X-rays produced by the linear accelerator, a total of 7,871 metaphase spreads were counted, and all unstable chromosomal aberrations
found were recorded.
of heptaplatin significantly reduces the mitotic indices and highly significantly induces chromosomal aberrations
(both numerically and structurally) in proliferative bone marrow cells of SWR/J mice.
Effect of hydrocortisone and MEGT on chromosomal aberration
in mouse spermatocytes.
Assessment of genotoxicity of Imidazole using bone marrow mesenchymal stem cells by chromosomal aberration
frequency in lymphocytes predicts the risk of cancer: Results from a pooled cohort study of 22 358 subjects in 11 countries.
The MI inhibition and induction of chromosomal aberration
in plant cells by several pesticides have been reported earlier by different workers [28,29].
Suitable biomarkers include, among others, PAHDNA adducts, markers of oxidative stress, and chromosomal aberration