Clinically, the differentials are lupus vulgaris, pyoderma gangrenosum, and deep fungal infection like chromoblastomycosis. Hence, tissue culture and histopathology are mandatory to come to a final diagnosis.
Of the two main aetiological agents of chromoblastomycosis, Cladophialophora carrionii is thought to be endemic in semiarid zones while Fonsecaea pedrosoi is seen more in humid tropical climates.(2) The disease occurs predominantly in males (70%).
Although it can be used for infections caused by Candida, the primary indication is for mild to moderate endemic mycoses, such as paracoccidioidomycosis, histoplasmosis, coccidioidomycosis, blastomycosis, chromoblastomycosis, phaeohyphomycosis and sporotrichosis, in addition to dermatomycosis.