Although curvature contributions have also been ascribed to phosphatidic acid (PA) in chromaffin cells
(Zeniou-Meyer et al.
Hains BC, Chastain KM, Everhart AW, McAdoo DJ, Hulsebosch CE, "Transplants of Adrenal Medullary Chromaffin Cells
Reduce Fore Limb and Hind Limb Allodynia in a Rodent Model of Chronic Central Pain after Spinal Cord Hemisection Injury", Exp.
This raises the questions of how much of the plasticity remains in later stages of ageing, and what mechanisms are involved in this loss of chromaffin cell
Immunoisolated xenogenic chromaffin cell
therapy for chronic pain.
Lack of COMT in sympathetic nerves, where most norepinephrine is initially metabolized, means that the metanephrines are relatively specific markers for catecholamines produced in chromaffin cells
and their tumor derivatives.
Bovine chromaffin cells
were isolated following published methods (Mao et al.
Molecular cloning of endopin 1, a novel serpin localized to neurosecretory vesicles of chromaffin cells
Each part of adrenal gland has different cell types: cells producing sexual steroid hormones, glucocorticoids and mineralocorticoids are present in the cortex, and chromaffin cells
, which are producers of catecholamine and neuropeptides are present in medullar region (Hincu et al.
The former is represented by neuroblastoma and ganglioneuroblastoma that arise from primitive sympathetic ganglion cells and the latter is represented by pheochromocytoma that arise from chromaffin cells
Pheochromocytoma refers to a tumor originating in the catecholamine producing chromaffin cells
, located mainly in the adrenal medulla.
Pheochromocytoma is a rare and mostly benign tumor which arises from chromaffin cells
with excessive catecholamine production and secretion.
In the storage vesicles of noradrenergic nerves and chromaffin cells
, dopamine [beta]-hydroxylase converts dopamine to norepinephrine.
Tympanic paragangliomas are neuroendocrine neoplasms located in the middle ear and arising from chromaffin cells
of the parasympathetic paraganglia.
A phaeochromocytoma is a rare neuro-endocrine tumour of the paraganglionic chromaffin cells
affecting 2-8 persons per million per year.
The specific aims of this proposal are: 1) to characterize the alpha6-containing nAChR subtype(s) present in human adrenal chromaffin cells
and to investigate the regulation of their expression by nicotine; 2) to study the functional interaction between alpha6beta4 nAChRs and mitochondria; 3) the regulation of this nAChR subtype by mitochondrial ROS.