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There is no standard method for the treatment of choroidal osteoma. Patients must be followed regularly and secondary complications must be treated as appropriate.
It is believed that laser photocoagulation may not have adequate efficacy in cases of CNV secondary to choroidal osteoma due to insufficient tumor melanine and a thinned, degenerated RPE-Bruch's membrane complex.
(5,6) It is thought that in choroidal osteoma cases, normal tissues are also damaged during the process, and VEGF expression is increased as a result of choroidal and retinal ischemic stress and chronic inflammation.
The first reported use of intravitreal ranibizumab injection for CNV secondary to choroidal osteoma was by Song and Roh (5) in 2009; they found that CNV had regressed and visual acuity had improved from 20/200 to 20/100 at 6 months post-injection.