2% had an experience of Chorionic villus sampling
among which 20% abortions were reported.
Keywords: Amniocentesis, chorionic villus sampling
, cordocenteses, prenatal genetic diagnostic testing
Currier and his colleagues found that about a third of patients with a first- or second-trimester positive cfDNA test opted for diagnostic testing with either chorionic villus sampling
Instruments for chorionic villus sampling
for prenatal diagnosis.
DISCUSSION: Chorionic villus sampling
has emerged as the only safe invasive prenatal diagnostic procedure in the first trimester.
But it identifies fewer chromosomal abnormalities than combination screening or the more invasive chorionic villus sampling
The only definitive test involves chorionic villus sampling
and amniocentesis but that carries a risk of miscarriage.
Existing invasive diagnostic tests -- Chorionic villus sampling
(CVS) and amniocentesis, which use samples from the developing placenta, are still only 75-90 per cent accurate with a risk of miscarriage," he said.
Other existing methods for detecting the condition - which causes physical and learning disabilities and raises the risk of heart disease - are amniocentesis, in which a needle is inserted into the womb to remove amniotic fluid, and chorionic villus sampling
, whereby a piece of placenta is taken for genetic testing.
KEY WORDS: b-thalassaemia, Prenatal diagnosis, Chorionic villus sampling
Achievement of that goal will reduce appreciably the numbers of invasive prenatal diagnostic procedures and potentially banish the techniques of amniocentesis and chorionic villus sampling
to the history books.
Despite the decrease in HIV transmission with antiretroviral cover, procedures such as chorionic villus sampling
and cordocentesis should still be avoided in the HIV-infected woman as the risk of transmission to the fetus may be considerably higher.
At present the only other way to diagnose these diseases is to do amniocentesis or chorionic villus sampling
, both of which carry a small risk of miscarriage.
4) The Royal College of Obstetricians and Gynaecologists guideline on amniocentesis and chorionic villus sampling
advises that patients should be informed of an additional 1% risk of fetal loss following an amniocentesis, and a slightly higher risk following chorionic villus sampling
Genetic tests performed on the mother during the pregnancy (for example, amniocentesis, chorionic villus sampling
, sonograms, and/or biochemical screening tests) also are important.