virus: a prenatal and postnatal threat.
IHC results were negative for lymphocytic choriomeningitis
virus, measles virus, and T.
virus: emerging fetal teratogen.
virus in southern France: four case reports and a review of the literature.
Isolation of lymphocytic choriomeningitis
virus from wild house mice (Mus musculus) in Osaka Port, Japan.
In Africa, Lassa virus (LASV) and Lujo virus are the only known members of the family Arenaviridae that cause human disease (2,3); however, evidence for lymphocytic choriomeningitis
virus, another Arenaviridae sp., was recently reported in Gabon (4).
All four organ recipients subsequently were found to have evidence of infection with lymphocytic choriomeningitis
virus (LCMV), a rodent-borne Old World arenavirus.
RANTES--mice infected with lymphocytic choriomeningitis
virus show decreased CD8+ T cell cytokine production and cytotoxic ability coincident with higher viral loads (22).
Other possible causes of encephalitis (e.g., herpes simplex; arboviruses and enteroviruses; lymphocytic choriomeningitis
; measles; and bacterial, fungal, and parasitic infections [e.g., toxocariasis and cysticerc osis]) were excluded based on direct examination, culture, serology, and polymerase chain reaction (PCR) testing of blood and CSF.
Cases have been caused by emerging pathogens, including West Nile virus (WNV) (7, 8), rabies virus (9), lymphocytic choriomeningitis
virus (LCMV) (10), and Balamuthia mandrillaris amebae (11).
The Old World arenaviruses include the agents of Lassa fever and lymphocytic choriomeningitis
Serum samples were tested for IgG against WWAV, Amapan virus (AMAV), an arenavirus that is antigenically closely related to the Tacaribe serocomplex viruses known to cause hemorrhagic fever (4), and lymphocytic choriomeningitis
virus (LCMV), the prototypical arenavirus and member of the Lassa-lymphocytic choriomeningitis
serocomplex, by using an ELISA.
Additional serologic tests found no significant reactions to other arthropodborne and zoonotic pathogens, including New World arenaviruses, lymphocytic choriomeningitis
virus, hantaviruses, other Bunyaviridae, Filoviridae, Flaviviridae, Rhabdoviridae, Togaviridae, spotted-fever-group and typhus-group rickettsia, Ehrlichia chaffeensis, and Coxiella burnetii.
Molecular testing results were negative for rickettsiae, filoviruses (Marburgviruses and Ebolaviruses), selected bunyaviruses (Rift Valley fever virus, Crimean Congo hemorrhagic fever virus), arenaviruses (Lassa, Lujo, and lymphocytic choriomeningitis
viruses), and several arbo-viruses (yellow fever, dengue, O'nyong-nyong, chikungunya, and Zika viruses).
virus (LCMV), a rodentborne arenavirus, is a rare, zoonotic cause of aseptic meningitis in Europe and North America.