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Related to chondromyxoid fibroma: chondroblastoma
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Chondromyxoid fibroma is another intermediate type of cartilaginous tumor that may be misinterpreted as a CBT.
Chondromyxoid fibroma (CMF) is a slowly growing, benign bone tumor that is exceedingly rare within the temporal bone.
Lorenz diagnosed a chondromyxoid fibroma, a non-malignant bone tumor that usually occurs in the limbs and feet.
The spectrum of these lesions includes enchondroma, osteochondroma, hemangioma, hemangiopericytoma, enostosis, osteoid osteoma, fibrous dysplasia, Paget disease, Langerhans cell histiocytosis, aneurysmal bone cyst, eosinophilic granuloma, giant cell tumor, brown tumor, nonossifying fibroma, and chondromyxoid fibroma.
Others benign tumours were chondroma, osteochondroma, osteoma and chondromyxoid fibroma.
Review of the histology (figure 2, A) suggested a low-grade malignancy, and the diagnosis of a low-grade chondromyxoid neoplasm was made, with a differential diagnosis of chondromyxoid fibroma, chondrosarcoma, and chondroblastic osteosarcoma.
15,18) Primary lesions most frequently associated with ABC (in order of frequency) include giant cell tumor of bone, chondroblastoma, chondromyxoid fibroma, and fibrous dysplasia, particularly in pregnancy.
Fine needle aspiration cytology of chondroblastoma and chondromyxoid fibroma.
Brachyury staining was further performed in the following 2 categories: (1) 58 nonchordomatous tumors, which included 26 chondroid tumors (4 cases of grade I chondrosarcoma, 9 cases of grade II chondrosarcoma, 3 cases of grade III chondrosarcoma, 2 cases of chondromyxoid fibroma, 1 chondroblastoma, 4 osteochondromas, and 2 cases of extraskeletal myxoid chondrosarcoma), 7 liposarcomas, 5 rhabdomyosarcomas, 4 pleomorphic adenomas, 4 mucoepidermoid carcinomas, 4 mucinous adenocarcinomas, 6 germ cell tumors, and 2 cases of renal cell carcinoma (Table 2); and (2) 7 unrelated miscellaneous tissues, which included normal cartilage derived from trachea (2 cases), articular surface (1 case), and testicular tissue (4 cases).
The matrix of chondromyxoid fibroma may sometimes resemble chondroblastoma, and both lesions can contain numerous osteoclast-like giant cells.