Efficacy and safety of a modified killed-whole- cell oral cholera vaccine
in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial.
We were not able to implement the campaign exactly as planned, because of a concurrent national vaccination campaign, which targeted newborns through children aged 9 years and also included the polio vaccine (polio and cholera vaccines
must be administered 2 weeks apart because of possible interactions).
If the demonstration were deemed successful, we would suggest production of cholera vaccine
be ramped up for use across Haiti--perhaps in conjunction with childhood immunization programs--and in other countries (and possibly for the development of a global stockpile).
Few studies have examined the value of cholera vaccines
in controlling cholera outbreaks.
Nair: Only one cholera vaccine
is available in the Indian market.
Market research studies conducted with travel medicine clinics have shown a strong preference for a combined vaccine compared to either ETEC or cholera vaccines
These statements also include statements regarding: (i) AVANT's expectations regarding its restructuring and quarterly cash burn rate, (ii) AVANT's expectations regarding the proposed merger with Celldex (iii) AVANT's expectations of royalty payments from PRF related to Rotarix, (iv) AVANT's expectations regarding its own sponsored double-blind, placebo-controlled Phase 2 dose-ranging trial of Ty800 and the NIH-sponsored Phase 1 trial of its ETEC Cholera vaccine
candidate, and (v) statements made regarding AVANT's goals for its programs and products.
Strong evidence would support use of cholera vaccines
in disease-endemic settings, and an evolving body of evidence, largely from increased interest in cholera after its appearance in Haiti, suggests that cholera vaccines
might be beneficial in reactive situations, i.
Crucell also markets travel vaccines, such as the only oral anti-typhoid vaccine, an oral cholera vaccine
and the only aluminum-free hepatitis A vaccine on the market.
The newly-added sales of the blue ear disease vaccine and the hog cholera vaccine
reached nearly RMB700 million in 2007.
For instance, tick-borne encephalitis vaccine and cholera vaccine
, which are described in this chapter, are available in Europe but not in the United States.
An oral cholera vaccine
showing close to 80% protective efficacy in
This vaccine builds on the clinical successes to date of our single-dose, oral cholera vaccine
, and represents the next important milestone towards our goal of developing a safe, oral, rapid-acting "super enteric" vaccine that combines protection against multiple diseases in a single product.
Development of a safe, effective cholera vaccine
is the first step in establishing AVANT's travelers' vaccine franchise.
Taylor also served at the Armed Forces Research Institute of Medical Sciences in Bangkok, Thailand, and was Director of the Cholera Vaccine
Project at the Naval Medical Research Institute detachment in Lima, Peru.