Abbreviations FSC: Fusarinine C MG: Minigastrin CCK2: Cholecystokinin
receptor subtype 2 PET/CT: Positron emission computed tomography RT: Room temperature DOTA: 1,4,7,10-Tetraazacyclododecane-1,4,7,10 tetraacetic acid DTPA: Diethylene triamine pentaacetic acid PBS: Phosphate buffered saline BSA: Bovine serum albumin HEPES: 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid buffer TRIS: Tris-(hydroxymethyl)aminomethane EDTA: Ethylenediaminetetra acetic acid RP-HPLC: Reversed-phase high-performance liquid chromatography TLC: Thin layer chromatography p.i.: Postinjection.
Alterations in brain cholecystokinin
receptors after fasting.
 showed that heartburn, abdominal discomfort, and nausea increased significantly during lipid infusion in GERD patients, and this finding is to be linked with an enhancement of chylomicron production and secretion that may stimulate release of cholecystokinin
, an activator of vagal afferents.
The gene-specific oligonucleotide primers for growth hormone (gh), growth hormone receptor (ghra), insulin-like growth factor 1a (igf-1a), insulin-like growth factor receptor a and b (igf-1r a and b), insulin-like growth factor binding protein 1 (igfbp-1), ghrelin (ghrl), cholecystokinin
a (cck) and glucokinase (gck) were developed using Primer-BLAST (NCBI) (Ye et al., 2012).
(99-101) Mice deficient in T7 trypsinogen exhibit a marked reduction in activation of trypsinogen but nevertheless exhibit comparable levels of acute and chronic experimental pancreatitis induced by repeated injections of cerulein, a cholecystokinin
receptor (CCKR) agonist as observed in wild type mice.
To narrow down their search, Medrihan and Sagi focused on a particular group of cells called cholecystokinin
(CCK)-expressing neurons in the part of the brain known as the dentate gyrus.
Ethanol diet increases the sensitivity of rats to pancreatitis induced by cholecystokinin
(10) Also, postprandial cholecystokinin
and stomach relaxation after food consumption are known to be diminished in BN.
(37) For nutrition, unlike the stigma relating them to anti-nutritional effects, these inhibitors have a heterologous and bioactive role in the protein digestion process, presenting effect in satiety control with consequent weight reduction in experimental model, considering that, from the decrease of the free trypsin activity and consequent reduction of the breakdown of proteins and peptides, there is an increase in the concentration of the satiety hormone CCK (cholecystokinin
and gut-brain signalling," Regulatory Peptides, vol.
Three main types of perisomatic interneurons can be distinguished in the human hippocampus: parvalbumin(PV-) positive axo-axonic or chandelier cells, PV-positive basket cells, and Type 1 cannabinoid receptor- (CB1-) positive basket cells also containing cholecystokinin
Furthermore, soy protein promotes the secretion of cholecystokinin
, a gastrointestinal hormone that reduces appetite .
HIDA scan was consistent with biliary dyskinesia with an ejection fraction of 8% after infusion of cholecystokinin
, and she subsequently underwent laparoscopic cholecystectomy.
This is where the diagnosis is based on characteristic symptoms and abnormal GB function, typically revealed by cholecystokinin