cerivastatin


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  • noun

Synonyms for cerivastatin

an oral drug (trade name Baycol) to reduce blood cholesterol levels

References in periodicals archive ?
The risk of rhabdomyolysis is not clearly related to the LDL-lowering efficacy; for example, cerivastatin (Now withdrawn) was not particularly effective, but was much more likely than other statins to cause rhabdomyolysis.
The former group which can readily cross the BBB includes simvastatin, atorvastatin, and cerivastatin while hydrophilic statins include rosuvastatin and pravastatin [131].
Although cerivastatin (Baycol) was withdrawn from the market because of 60 deaths from rhabdomyolysis, (17) more than 1,000 deaths with atorvastatin and rosuvastatin did not cause such concern, probably because they were labeled as acute kidney failure deaths.
Previous products liability cases implicating statins have famously involved cerivastatin (Baycol), a one-time rival to Lipitor, for causing rhabdomyolysis.
We assembled secondary prevention cohorts, which included patients who were admitted to a hospital between 1 January 1998 (or one year after the beginning of data availability) and 31 March 2011, who received a coded diagnosis (principal or secondary) for acute myocardial infarction or stroke or a procedure for coronary artery bypass graft or percutaneous coronary intervention during their stay in hospital, who had no record of a diabetes diagnosis during their hospitalisation, and who then received a statin prescription within 90 days after being discharged, having not been prescribed a cholesterol lowering drug in the previous year (World Health Organization Anatomical Therapeutic Class C10, cerivastatin excluded).
Sugiyama, "Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil," The Journal of Pharmacology and Experimental Therapeutics, vol.
Metabolism of cerivastatin by human liver microsomes in vitro.
The synthetic cholesterol lowering statins such as fluvastatin (III) (Deslypere 1995), cerivastatin (Mc CleIlan and Lynda 1998) were synthesized on the basis of natural product lead, that is, mevastatin (IV) (Yamamoto et al.
Statins that belong to this group are Fluvastatin, Cerivastatin, Atorvastatin and Rosuvastatin
Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia.
One statin, cerivastatin (Baycol), was recalled a few years ago because it caused significant rhabdomyolysis and 31 deaths.
Cerivastatin reduces cytokine-induced surface expression of ICAM-1 via increased shedding in human endothelial cells.
n Baycol (Cerivastatin), prescribed to treat high cholesterol.
To date, the statin drug family has grown to include atorvastatin (Lipitor), cerivastatin (Baycol), fluvastatin (Lescol), pravastatin (Pravachol), rosuvastatin (Crestor) and simvastatin (Zocor).
Relative safety of gemfibrozil and fenofibrate in the absence of concomitant cerivastatin use.