One Shigella sonnei isolate (WA7593), cultured from a fecal specimen in August 2004, tested positive with an ESBL confirmatory disk diffusion panel (ceftazidime 24 mm, ceftazidime/clavulanate 32 mm, cefotaxime
14 mm, and cefotaxime
/clavulanate 34 mm; ).
In the present study, ceftazidime (30ug), cefotaxime
(30ug), ceftriaxone (30ug), cefpodoxime (10ug) and aztreonam (30ug) were used.
ESBL-producing Enterobacteriaceae were selected by the following criteria: susceptibility to cefoxitin; decreased susceptibility to cefotaxime
(30 [micro]g), ceftazidime (30 [micro]g), or cefepime (30 [micro]g) (zone diameter <21 mm); and enhanced susceptibility in the presence of clavulanic acid by the double disk synergy test (3).
The child's eyes were flushed with copious amounts of normal saline, and a dose of intravenous cefotaxime
and ampicillin was administered in the emergency department.
Choleraesuis isolates recovered from 7 patients, 2 were resistant to ampicillin and sulfamethoxazole-trimethoprim, 3 were resistant to chloramphenicol, 1 was resistant to ciprofloxacin, and all were susceptible to cefotaxime
These strains displayed MICs of cefotaxime
and ceftriaxone from 4 to 32 [micro]g/mL, exceeding the MICs of penicillin by as much as 5-fold (6).
The organism was susceptible to amoxicillin (MIC 1 mg/L), cefotaxime
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The patient was transferred to the intensive care unit, intubated, mechanically ventilated, and treated with intravenous fluids, dopamine, ampicillin, cefotaxime
, and vancomycin because of hypotension and pneumonia.
(30 ug) Plus Cefotaxime
and clavulanic Acid (30/10ug) b) Ceftizidime (30 ug) Plus Ceftizidime clauvalanic Acid (30/10ug) As per CLSI Guidelines Qty : 1000 Nos.
The faecal specimens from healthy individuals, patients, sewage sludge, cattle, chickens and raw meat (n = 122) were processed for microbiological analysis using MacConkey agar supplemented with cefotaxime
2 mg L-1 indole acetic acid and 400 mg L-1 cefotaxime
was found to be 100.
pneumoniae showed 100% resistance to amoxicillin-clavulanic acid, ceftazidime, ceftriaxone, cefotaxime
Against gram-negative bacteria, the following antibiotics were used: amikacin (30ug), (20ug of amoxicillin + 10ug of clavulanate), cefotaxime
(30ug), ceftazidime (30ug), cephalothin (30ug), chloramphenicol (30ug), ciprofloxacin (5ug), clindamycin (2ug), piperacillin (100ug) and tobramycin (10ug).