The matrix metalloproteinases (MMPs) play an important role in the process of cardiac remodeling by regulating structural integrity of the extracellular matrix. MMP-2 is one of the predominant MMPs expressed in the cardiac ventricles
. The altered expression of MMP-2 is shown to contribute to structural remodeling in pathological heart tissue., The purpose of the present study was to investigate the differences of MMP-2 expression between LVs and RVs in response to ND, swimming training (ST), and combined ND and ST (NS) in mice, based on their structural, functional, and biochemical characteristics.
One individual (a 7-month-old male) presented with a thin-walled pouch in the wall of the right cardiac ventricle
. A complete necropsy examination was performed, and samples of the heart (~0.5 cm) with evident macroscopic lesions were fixed in 10% neutral buffered formalin.
B-Type natriuretic peptide (BNP) and its co-released peptide N-terminal propeptide (NT-proBNP) are both secreted mainly by the left cardiac ventricle
as a consequence of pressure overload and wall stretch.
Individuals exposed to higher level of air pollutants were more likely to have larger cardiac ventricles
(main pumping chambers) after accounting for potential factors that can independently influence the size of these chambers, Aung said.
Weber, "Factors influencing the diastolic pressure-volume relation of the cardiac ventricles
," Federation Proceedings, vol.