Diagnosis of brain metastases is usually based on imaging techniques, but the diagnosis of carcinomatous meningitis
can be difficult.
An alternative diagnosis, including bacterial meningitis, Creutzfeld-Jakob disease, non-convulsive status epilepticus, acute disseminating encephalomyelitis, Brucella encephalitis, anti-NMDA receptor encephalitis, and carcinomatous meningitis
, was established in 13 (19.1%) patients.
Transitional cell carcinomatous meningitis
after M-VAC (methotrexate, vinblastine, doxorubicin, and cisplatin) chemotherapy.
consists of metastatic tumor cells involving the leptomeninges and the circulating cerebrospinal fluid; albeit, it is an uncommon complication of solid tumors.
Espinos et al., "The safety and efficacy of intrathecal liposomal cytarabine in patients with carcinomatous meningitis
from solid tumors," European Journal of Cancer Supplements, vol.