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Keywords: Computed tomography, Renal cell carcinoma, Sensitivity.
Renal cell carcinoma (RCC) is the commonest primary renal malignant tumour in adults and accounts for approximately 85-90% of renal malignancy1.
Adequate paraffin cell blocks for immunohistochemical studies were available for all 113 patients (94 serous carcinomas, 83.2% [93 high grade and 1 low grade]; 5 endometrioid adenocarcinomas [4.4%], 2 mucinous carcinomas [1.8%], 1 undifferentiated carcinoma [0.9%], 1 high grade neuroendocrine carcinoma [0.9%], and 10 carcinomas of unknown type [8.8%]).
Previous genome-wide analysis of ovarian serous carcinomas has shown frequent gains and amplifications on chromosome arm 3q26, and SOX2 has been implicated as a target gene of that region.
Papillary thyroid carcinomas show a female sex predilection.
Study of histological profile of papillary thyroid carcinomas associated with Hashimoto's thyroiditis.
Jacobson (1973) introduced a multifunctional system of malignancy which helped in finding of the tumour host relationship and analysing cell population carcinomas. Which is a more accurate evaluation of morphology of growth malignant tumours in head and neck area.14 Henson and Anneroth have reformed the histological system of grading which was established by Jacobsson et al for the use of carcinomas of tongue and mouth.15 Squamous cell carcinoma is graded as.
The role of hormonal treatment and targeted therapy against HER-2/neu with Herceptine is already being practiced for breast carcinoma, and gastric carcinomas including gastro-esophageal adenocarcinomas.6 Specific target therapy for these tumors are in practice now7 and response of targeted therapy for these tumors depends on their expression of HER 2/neu.8
Approximately 50% of the papillary carcinomas develop from the central part of the breast; nipple changes are observed in one-third of the patients (2, 3).
Kim, "Clinicopathologic significance of BRAF V600E mutation in papillary carcinomas of the thyroid," Cancer, vol.
P53 immunoexpression has not been found to be a reliable marker of high-grade transformation in acinic cell carcinomas [5,21].
Furthermore, since most of BRCA-related carcinomas of ovary originate in the fallopian tube, consideration may be given to performing a risk-reducing salpingectomy especially in young patients.
Urothelial carcinoma is most common in 6th or 7th decade of life but it is very rare in the younger age and only few cases have been reported.1 Its incidence of < 0.4% in the first two decades of life has been reported in a study by Javadpour and Mostofi.2 A more recent review of previous reports identified 125 patients who were aged <20 years, of whom only 20 were aged <10 years3 It usually presents with gross haematuria.4 Urothelial carcinoma in children is often low-grade lesions, solitary, non muscle invasive, low malignant potential and rarely recurrent.
Follicular carcinoma is another form of thyroid cancer.
Sarcomatoid variant of urothelial carcinoma (SVUC) of the renal pelvis is a rare tumour with aggressive clinical behaviour [3].