5-8 Historically, well-differentiated neuroendocrine neoplasms have been referred to as carcinoid tumors, a term which may cause confusion because clinically a carcinoid tumor is a serotoninproducing tumor associated with functional manifestations of carcinoid syndrome.
Carcinoid syndrome is characterized by frequent and debilitating diarrhea that often prevents patients from leading active, predictable lives, as well as by facial flushing, abdominal pain, heart valve damage and other serious consequences.
Nasdaq: LXRX) today announced that the pivotal TELESTAR Phase 3 clinical trial met its primary endpoint, showing the benefit of oral telotristat etiprate in treating cancer patients with carcinoid syndrome that is not adequately controlled by the current standard of care.
Euronext: IPN; ADR: IPSEY) today announced that they have entered into an agreement for Ipsen, upon regulatory approval, to commercialize telotristat etiprate in Canada, with a focus on the treatment of carcinoid syndrome.
The effects of carcinoid syndrome are severely debilitating for many people's lives, causing them to suffer from life-altering diarrhea, flushing and pain," said Lonnel Coats, Lexicon's president and chief executive officer.
Nasdaq: LXRX), a biopharmaceutical company focused on developing breakthrough treatments for human disease, today announced that it has completed enrollment in TELESTAR, its pivotal Phase 3 clinical trial of telotristat etiprate for patients with carcinoid syndrome.