Since insulin has pro-proliferative activity and activation of insulin signaling axis has been implicated in carcinogenesis
, [sup] some researchers proposed that the use of insulin by diabetic patients might contribute to cancer development.
ApcMin mice possess a heritable Apc gene mutation which is responsible for adenoma mutation and serve as a model for colorectal carcinogenesis
, the company added.
Methylation levels in DNA extracted from blood collected before diagnosis will be measured in a panel of CpG loci potentially involved in breast carcinogenesis
and in the DNA repetitive elements LINE-1 and Alu.
Animal models may reveal mechanisms of viral carcinogenesis
In addition, serum AA protein has a part in the development of carcinogenesis
Estos resultados permiten demostrar que la leche de bufala disminuye tanto el desarrollo de tumores como de lesiones displasicas de colon en un modelo de carcinogenesis
experimental del intestino grueso.
The expression profile of five of the proteins with validated or putative roles in the carcinogenesis
process, and for which antibodies against human forms of the proteins are available commercially was verified by western analysis.
National Toxicology Program (NTP) 2-year rodent toxicology and carcinogenesis
studies as the basis for an empirical study of the properties of different points of departure (PoD) for establishing human exposure guidelines to environmental agents.
The present study was undertaken to evaluate the combinatorial chemopreventive effects of bovine milk lactoferrin (bLF) and black tea polyphenols (Polyphenol-B) in a clinically relevant in vivo model of 7, 12-dimethylbenz[z]anthracene (DMBA)--induced male Syrian hamster buccal pouch (HBP) carcinogenesis
These studies suggest that COX-2 and PPAR-[gamma] are the regulatory molecules in the development of mammary carcinogenesis
He discusses how experimental leukemia research started and developed, the progress of cancer concepts, early research, research on avian leukosis and sarcoma virus, mouse and rat viruses, studies on stem cells and cytokines, viral and chemical carcinogenesis
, cell cycle control and centrosome, important oncogenes and suppressor genes and the related cell biology, skin carcinogenesis
, DNA viruses, and the common pathway for retroviruses and chemicals.
Barhoover was recognized with a Postdoctoral Research Award from both the SOT Molecular Biology Specialty Section and SOT Carcinogenesis
7) exhibited the strongest inhibitory effect and was selected to examine its effects on in vivo two-stage mouse skin carcinogenesis
induced by 7,12-dimethylbenz[a]anthracene (DMBA) as initiator and TPA as promoter.
Institute of Virology, Slovak Academy of Sciences (Bratislava, Slovakia) has patented methods that are prognostic for neoplastic/preneoplastic disease in a subject vertebrate, wherein said disease is associated with a tissue that normally expresses MN, but which MN expression is lost or diminished upon carcinogenesis
There have been many reports indicating that the deregulation of p21WAF1 is related to carcinogenesis
and the development of various tumors.