"OSA was independently associated with intracranial bone (calvaria
and skull base) thinning and not with extracranial (zygoma) thinning," the authors write.
(b) The numbers of TRAP-positive cells in the suture mesenchyme of calvaria
from the mouse groups administered with PBS, LPS, LPS with exendin-4, and exendin-4, respectively.
In contrast, MC3T3-E1 cells were established from newborn mouse calvaria
and have been shown to possess the features of normal osteoblasts.
A remarkable observation made during the first examination was a hypoplastic calvaria
, expressed as huge fontanels and an asymmetry of the cranial bones.
Other cell models, such as human osteosarcoma MG-63 [43, 106-108], mouse calvaria
osteoblastic cell line MC3T3-E1 [36, 95, 109-114], rat primary calvaria
cells [37, 40, 41, 45, 115, 116], primary human osteoblasts [42, 117-119], adipocyte-derived mesenchymal stem cells [118, 120-122], or bone marrow stromal cells [120, 123-133] were tested as well.
Cranial and facial features include frontal and parietal bossing, beaked nose, prominent eyes with blue sclera, hypoplasia of the maxilla and mandible, open fontanels and sutures, thick calvaria
, and hypoplastic paranasal sinuses [1, 2].
maxima potently stimulated osteoblastic differentiation and mineralization of MC3T3-E1 preosteoblast cells from mouse calvaria
compared both with normal mineralizing medium and dexamethasone (Rousseau et al.
Bi-parietal diameter and head circumference were measured in the axial plane having smooth and bilaterally symmetrical calvaria
and where the midline echo in the anterior third was broken by the cavum septi pellucidi with symmetrical appearance of both thalami.
Researches in mice have reported the activation of FXIII-A gene in osteocytes of long bones (femur) and flat bones (calvaria
Bosshardt et al., "Relative contributions of osteogenic tissues to new bone formation in periosteal distraction osteogenesis: histological and histomorphometrical evaluation in a rat Calvaria
," Clinical Implant Dentistry and Related Research, vol.
Torres and coworkers grafted DCPA and autologous bone granules separately into critical sized bone defects in rabbit calvaria
and after 8 weeks they found that the volumes of mineralized tissue formed by two kinds of granules were not significantly different [9, 10].
Osteoblast-like cells were obtained from the calvaria
of 20-day-old Lewis rats by the explant method.
AG can appear on skull radiography as radiolucent zones or as impressions on the inner table of the calvaria
. On CT AG can be hypodense or isodense relative to the brain parenchyma.
Sebaceous cysts, lipoma, fibroma, fibrous dysplasia, epidermoid cysts, dermoid cysts, lymphadenopathy, hidradenitis suppurativa, eosinophilic granuloma, Ewing's sarcoma, osteoma, and calvaria
should be considered at differential diagnosis.
Treatment of critical defects produced in calvaria
of mice with mesenchymal stem cells.