Calcium channel blockers
are responsible for more cardiovascular fatalities than any other cardiovascular agents in the USA, with an estimated 35% mortality rate.
Conclusion: Calcium channel blocker
(Verapamil) use with nitrate provided no significant difference in lowering radial spasm during coronary angiography.
The most widely prescribed antihypertensive agents in PINNACLE registry patients with TRH were beta-blockers, in 87%; ACE inhibitors, in 72%; calcium channel blockers
, in 71%; and thiazide diuretics, in 69%.
Of the many types of medications available to fight high blood pressure, calcium channel blockers
(CCBs) have emerged in recent years as an increasingly popular first-line drug to treat hypertension.
Side effects of calcium channel blockers
. Hypertension 1988;11(3):II42-4.
This study aimed to estimate the frequency of purpura and bleeding in patients on calcium channel blockers
and to look for an association between calcium channel blocker
therapy and petechiae due to capillary fragility induced by Hess test.
Despite a positive antinuclear antibody (ANA) and elevated sed rate (58) and rheumatoid factor (RF) in June and an ANA of 1:640 in August, it wasn't until November, when her sed rate was still 27 despite prednisone, that they decided it was most likely a reaction to one of her medications, probably hydralazine, and had her immediately stop the hydralazine and atenolol and continue on a calcium channel blocker
. About this same time, they started down titrating the prednisone, although it would take almost a year on prednisone before the positive ANA was resolved.
Aside from standard cardiopulmonary measures in calcium channel blocker
overdoses, additional commonly employed resuscitative therapies have included gastric lavage, multi-dose oral or nasogastric activated charcoal, flumazenil infusion, naloxone infusion, insulin and glucagon intravenous boluses, continuous calcium gluconate infusion, intravenous antiarrhythmics as indicated, and vasopressor support during mechanical ventilation.
Calcium channel blocking agents like verapamil, nifedipine and diltiazem are commonly used in the treatment of hypertension, angina, myocardial infarction and supraventricular tachycardia.6 Induction of hypercalcaemia through intravenous administration of calcium, is usually associated with increased gastric volume and acidity.7,8 The acid stimulating ability of calcium; is well known and there is extreme sensitivity to calcium in patients with Z-E syndrome.9,10 Calcium channel blocker
Verapamil may interfere with H+K+ ATP ase due to its high affinity for the site H+K+ATP ase system which is accessible from luminal side of the stomach.11
MET guidelines concur that alpha-blockers are effective, while there is insufficient evidence to recommend the regular use of calcium channel blockers
, corticosteroids, or PDE5 inhibitors as a monotherapy.
16 patients with calcium channel blocker
or beta blocker intoxication among 590 intoxication patients followed up in our pediatric intensive care unit between january 2011 and July 2012 were included in the study.
Calcium channel blockers
are widely used for their antihypertensive effects especially in the elderly patients3.
(4) More patients taking an ACE-I plus a calcium channel blocker
achieved the primary end point (reductions in systolic blood pressure [greater than or equal to] 25 mm Hg) than did patients randomized to monotherapy (74.2% vs 53.9%; NNT=5).
The medical treatment of ES includes calcium channel blockers
, nitrates, tricyclic antidepressants, smooth muscle antispasmodics, and/or sildenafil.
TWYNSTA is a single pill combination of two blood pressure medications, telmisartan (an angiotensin II receptor antagonist or ARB) and amlodipine (a dihydropyridinic calcium channel blocker
, or long-acting CCB).