Efficacy of broncho-alveolar lavage and bronchial brush cytology
in diagnosing lung cancers.
The performance characteristics of bile duct brush cytology
were determined for all specimens including those with cytologic diagnoses of negative, atypical, suspicious (for malignancy), and malignant categories both individually and for the latter 3 categories as a combined group.
During the period from February 2012 to February 2013, 84 cases with suspected malignant stricture of bile duct were diagnosed satisfactorily through intraductal ultrasonography (IDUS), endoscopic brush cytology
and K-ras, P53 gene mutation detection, and results are reported as follows now.
Twelve consecutive patients with documented main pancreatic duct stricture were investigated by endoscopic ultrasonography (EUS) and ERCP, followed by brush cytology
and OcT scanning.
probes were taken from the noses of 194 male, nonsmoking customs officers twice a year (January and July) over a period of 5 years.
Conventional endoscopic retrograde cholangiopancreatography (ERCP) brush cytology
, for example, has a mere 30%-70% sensitivity for diagnosis of cholangiocarcinoma.
Oral brush cytology
was performed in all the 60 cases.
(107) The biliary tract is frequently sampled by brush cytology
, allowing for cytologic analysis as well as fluorescent in situ hybridization (FISH) and molecular studies (see section below).
We got positive results in 25 patients with 68% diagnostic yield through BAL cytology, brush cytology
, and bronchoscopy-guided endobronchial biopsy.
In Mossa et al .'s study, the patients undergoing D & C had higher pain scores compared with those who underwent brush cytology
. [sup] For these reasons, D & C is not an ideal screening method.
It is of utmost importance to perform as much sampling of tissue from bronchial tree by combining procedures such as bronchial washings, bronchial brush cytology
and cell block of bronchial washings to maximise the diagnostic yield.
The true and false positives and negatives were based on the following: (i) True positive: Samples that were positive on both histology and brush cytology
. (ii) True negative: Samples that were negative on both histology and brush cytology
(1-3) For example, brush cytology
of pancreaticobiliary strictures has a specificity approaching 100%, but a sensitivity ranging from 37% to 89%, with an average of 59%.