The performance characteristics of bile duct brush cytology were determined for all specimens including those with cytologic diagnoses of negative, atypical, suspicious (for malignancy), and malignant categories both individually and for the latter 3 categories as a combined group.
During the period from February 2012 to February 2013, 84 cases with suspected malignant stricture of bile duct were diagnosed satisfactorily through intraductal ultrasonography (IDUS), endoscopic brush cytology and K-ras, P53 gene mutation detection, and results are reported as follows now.
It is of utmost importance to perform as much sampling of tissue from bronchial tree by combining procedures such as bronchial washings, bronchial brush cytology and cell block of bronchial washings to maximise the diagnostic yield.
The true and false positives and negatives were based on the following: (i) True positive: Samples that were positive on both histology and brush cytology. (ii) True negative: Samples that were negative on both histology and brush cytology.