Urinary trehalase comes from the apical membranes of the renal proximal tubular cells: immunohistochemical staining of the renal cortex-mix shows the existence of this enzyme on the
brush border of the renal proximal tubules (Fig.
Protein-lipid interactions in human small intestinal
brush border membranes.
However, these results do not demonstrate a localization of GLUT2 to the
brush border membrane in ruminants.
The body loses part of this combined amount, and the remainder is ultimately transferred to the blood via the
brush border site.
Histopathological changes in kidney of diabetic rat showed signs of tubular necrosis with loss of their
brush border, vacuolar degeneration of proximal tubules and thickened basement membrane.
Hence, the potential anti-diabetic effect of CM was studied using four in vitro models: (a) intestinal
brush border membrane vesicles (BBMV), for studying intestinal glucose absorption; (b) rat hepatoma cell line H4IIE, for studying hepatic glucose production; (c) human skin fibroblast cell line Hs68, for studying cellular glucose uptake by glucose transporter 1 (Glut1); and (d) mouse adipocytes 3T3-L1, for studying cellular glucose uptake by glucose transporter 4 (Glut4).
Almost all parts of the digestive tract show positive AP activities restricted at the
brush border of the epithelial cells or in the lumen.
DCYTB localizes to the intestinal
brush border and its expression is amplified during iron deficiency, ineffective erythropoiesis, and hypoxia.
It is sequestered in the wall of the small intestine and sits on the
brush border membrane surfaces of enterocytes.
Goblet cells containing predominantly intestinal-type mucin were scattered throughout the lesion, and many of the columnar surface epithelial cells had a distinct
brush border.
A/E pathogens typically reside on a pedestal on the surface of the host epithelial cell and ultimately cause severe disruption of the microvilli
brush border (Figure lA).
