Brown fat tissue
is important in thermogenesis and energy metabolism.
A team of researchers, led by Bruce Spiegelman of the Dana Farber Cancer Institute and Harvard Medical School in Boston, Mass., made brown fat tissue
from the skin cells of mice and mouse myoblasts.
Researchers grew "beating" cells with properties similar to the heart's conductive tissue from stem cells taken from the brown fat tissue
When body temperature drops below a regulatory threshold, brown fat tissue
is highly specialized for nonshivering thermogenesis.
"We already know that those of us who have more brown fat tissue
have a smaller risk of developing type 2 diabetes.
In addition, the researchers found that SIRT1 must be present in POMC neurons for leptin to stimulate the remodeling of white adipose tissue into brown fat tissue
, which "burns" fat to generate heat.