The potential is there for us to develop safe and effective ways of activating this brown fat
to promote weight loss and increase energy expenditure - but we need more data to be able to get to that point," Dr Thomas Barber, from the Department of Metabolic and Vascular Health at Warwick Medical School, said.
It's long been thought that brown fat
was present only in infants and small mammals, and that white fat was present in adults, but research shows that most adults have some brown fat
burns energy instead of just storing it the way white fat does.
Research suggests that people who find it easy to stay slim have more brown fat
cells than individuals prone to weight gain.
Unlike "white" adipose fat, brown fat
contains large numbers of mitochondria - tiny biological power plants that burn sugar from food to provide energy for cells.
When you were born, you had a pad of brown fat
on your back, and it helped you control your body temperature.
What this means is that fucoxanthin can help white adipose tissue mimic some of the thermogenic properties of brown fat
, ultimately resulting in a safe increase in metabolic rate and enhanced fat- burning.
Not only do these findings identify TRPV4 as a compelling therapeutic target, but they continue to build out our understanding of the role of brown fat
in humans and in developing novel brown fat
treatments for metabolic disease.
Studies show that the fully activated brown fat
generates 300 times more heat than any other tissue in the body.
The lead author of the study and the principal research fellow head from the Department of Biochemistry and Molecular Biology at Monash University, Professor Tony Tiganis, said that a new approach to develop weight loss agents was turning the white fat into brown fat
In tests on mice it lowered cholesterol, controlled blood sugar and turned unhealthy white fat into easily burned brown fat
Weinreb said, "Research into human brown fat
to date has suggested that brown fat
is correlated with the maintenance and regulation of metabolism .
This unique in vitro human stem cell model of brown fat
tissue could aid studies into how fat tissue develops and the development of new anti-obesity drugs.
6 ( ANI ): Researchers have found a gene regulator called microRNA-133, which induces adult muscle stem cells to turn into muscle fiber and brown fat
However, several hypotheses have been suggested, such as a defect in adrenergic-stimulated lipolysis, resulting in autonomy and massive proliferation of lipomatous cells; embryologic brown fat
undergoing functional sympathetic denervation; or a primary defect in brown fat