By utilizing GSK's larger sales force infrastructure, we can broaden our exposure to the patients who suffer from breakthrough seizures
, and the physicians who treat them, and potentially help these patients avoid a trip to the emergency room.
ARS occurs in a small subset of patients with epilepsy who regularly experience breakthrough seizures
in flurries or clusters, despite treatment with a regimen of anti-epileptic drugs.
Willy is still on several medications and has breakthrough seizures
today announced that the United States Food and Drug Administration (FDA) has cleared an Investigational New Drug application (IND) to commence clinical trials advancing the development of NRL-1 for the treatment of acute breakthrough seizures
The results from this pilot study are very encouraging," commented Jim Cloyd, PharmD, University of Minnesota professor and principal investigator of the study, "The only approved drug to treat breakthrough seizures
outside the hospital is diazepam rectal gel, a therapy that many older children and adults decline to use.
Patients should strive for a more individualized treatment plan by sharing a daily diary or record of how they are feeling, any medication side-effects or breakthrough seizures
they experience with their healthcare professional.
ARS, also called seizure clusters, occurs in a small subset of patients with epilepsy who regularly experience breakthrough seizures
in flurries or clusters despite treatment with a regimen of anti-epileptic drugs.
Access to medication can be a life-and-death issue for people with epilepsy due to the potential for breakthrough seizures
when drug levels in the blood fall below therapeutic levels.
Notwithstanding the potential risks, it is of utmost importance that patients with epilepsy do not stop their medication without first consulting their doctor as this may lead to breakthrough seizures
that could have harmful and even fatal consequences for both the mother and baby.