In fact, the heparin-induced cascade effect of fatty acids on the serum binding of ketoprofen, which is bound to
site II on HSA, was also observed for the fatty acid-indole uremic toxin-ketoprofen system .
Among seven people with sickle-cell disease and five without it, breathing various concentrations of nitric oxide did not change the affinity with which sickle hemoglobin bound to oxygen in blood drawn from the test subjects, Gladwin and his colleagues reported in the October 1999 JOURNAL OF CLINICAL INVESTIGATION.
The team found that breathing nitric oxide did increase the hemoglobin bound to nitric oxide.
By comparing how much natural hormone bound to the receptors or binding proteins-with and without the pollutant-he was able to measure the binding of the pseudohormone.
While there were no surprises among the compounds that bound to the estrogen receptor, Danzo says he was amazed to see how many pollutants bound to the androgen receptor: DDT and three of its breakdown products, two ingredients of lindane (gamma- and delta-HCH), dieldrin, atrazine, and pentachlorophenol.
Torkild Andersen and his collaborators are using the new storage ring ASTRID at Aarhus University in Denmark to investigate the weak interactions of electrons loosely bound to
atoms and simple molecules.
Wilson and his Scripps colleagues used another approach: They coaxed labgrown fruit fly cells into manufacturing empty MHC-I molecules, which the researchers bound to
But when the researchers mixed TCDD and the receptor with fluid taken from ground-up cells, the complex indeed bound to
Lerner and his co-workers spotted what looked like DNA bound to
the cell membranes.
Riggs' team added radioactively labeled estrogen to bone cells, then counted how many estrogen molecules bound to
sites in the nuclei.
He reports that the six-carbon sugar alpha galactose -- a common sugar that, when bound to
glucose, makes the milk sugar lactose -- appears to be the critical link to sperm recognition.