It shows 50% (9/18) cases of Lymphomatous infiltration and all the cases (3/3) of Chronic Granulomatous Inflammation were labeled as normal marrow on bone marrow aspiration.
Examination of the bone marrow is one of the diagnostic pillars of haematological practice.
Bone marrow aspiration and trephine biopsy complement each other and in many centers both the specimens are obtained at the same time and from the same site1, 11.
In our study 100 % case (03/03) of Granulomatous inflammation in the bone marrow were diagnosed on trephine biopsy and none of the case was diagnosed on bone marrow aspirate.
All the cases of Myelofibrosis (07/07) were diagnosed on trephine biopsy and the bone marrow aspirate was unsuccessful in all cases due to marked fibrosis.
Bone marrow biopsy remained the gold standard for diagnosing Aplastic Anaemia.
Bone marrow aspiration and trephine bone biopsy complement each for bone marrow evaluation.
Bird AR, Jacob P, Trephine biopsy of the bone marrow.