In cases of acute and severe haemodynamic fluctuations, the following medical interventions were taken: i) bradycardia (Heart rate <60 beats/min), bolus dose
of 0.6mg atropine IV; ii) hypotension (MAP<60mm Hg), increased rate of infusion of IV fluid and/or bolus dose
of phenylephrine 100mcg IV and; iii) hypertension (MAP>110mm Hg) bolus dose
of labetalol 5mg IV.
This patient had hypotension and required two bolus doses
of ephedrine 5 mg.
This double-blind randomised controlled trial was designed to determine if a single bolus dose
of ketamine 0.25 mg/kg administered in the recovery room to patients with pain resistant to two doses of a standard morphine pain protocol, appreciably improves analgesia at rest and four hours post-operatively, compared to controls who receive morphine alone.
IV supplementation converted to normal saline intraoperatively to take care of glycemia and avoiding hyperglycemia, due to increased secretion of counter regulatory hormones like catecholamine, cortisol, glucagon and growth hormone. Fentanyl considered safe as its effect after single bolus dose
is terminated by redistribution to muscle and fat; subsequent metabolism is primarily by N-dealkylation and dehydroxylation but not by conjugation.
In an uncontrolled study using intrathecal baclofen (24) in 10 patients, intermittent daily bolus doses
between 200 and 1000 [micro]g were used.
severe hypotension (<80% of basal) not responding to Ephedrine bolus doses
(treated with Epinephrine), recurrent hypotension despite cumulative Ephedrine bolus doses
in excess of 60mg (treated with additional 10pg of Phenylephrine) and extreme tachycardia (>30% of basal, treated by stopping Ephedrine infusion) or bradycardia (<60/min, treated with Inj.
The first cohort in malignant brain tumor patients received a 15mCi/m2 bolus dose
of CLR 131 and based on results, the company is progressing to a second cohort of patients, who will receive a higher 30mCi/m2 bolus dose
of CLR 131.
Group V patients were given Vecuronium (0.1 mg/ kg) bolus dose
and Group A patients were given Atracurium (0.5 mg/kg) bolus dose
Esmolol ([beta]-blocker) infusion was started with a dose of 150 [micro]g/kg/min following an intermittent bolus dose
of 30 mg to a total bolus dose
of 150 mg, and shortly after, she reverted to sinus rhythm.
Plain abdominal radiographs were taken at an initial and after the bolus dose
applications at the 3rd, 8th, and 24th hours.
A single bolus dose
provides approximately 10 min of anaesthesia, with complete recovery occurring within 20 to 30 min in dogs and cats (Maney et al., 2013).
The result of our study showed that slower administration of oxytocin can successfully lessen the cardiovascular adverse events of a bolus dose
Remifentanil is an opioid, reaching its peak effect quickly after a bolus dose
. It provides easily titratable analgesia, bradycardia and vasodilation (5).
A total of 5,110 participants aged 50 to 84 years were randomized to receive vitamin D3 (2,558 adults; initial bolus dose
of 200,000 IU followed by monthly doses of 100,000 IU) or placebo (2,552 adults) for a median of 3.3 years; 5,108 were included in the primary analysis.
In our study, we compared the efficacy of dexmedetomidine 0.5 [micro]g/kg and dexmedetomidine 1 [micro]g/kg as single bolus dose
for smooth removal of LMA in children.