In our patient, the elevated blood ammonia
level and the rapid resolution of symptoms coupled with the reduction of his blood ammonia
level led us to suspect that hyperammonemia may have accounted for his presentation.
In general, implantation of a new liver results in normalization of blood ammonia
concentrations as well as in significant improvements in cognitive function in these patients (Arria et al.
levels were consistently elevated, up to 130 [micro]mol/L (normal 15-60 [micro]mol/L).
Among the most serious allegations against the Penn program was that Gelsinger never should have been treated because his blood ammonia
levels were too high the day before he received an infusion of corrective genes.
He also attempted to measure blood ammonia
and introduced Jaffe's alkaline picrate method for creatinine.
In addition, the physician can use two medications (lactulose and neomycin) to control blood ammonia
Carriers have enough functional enzyme under most circumstances but may succumb to high blood ammonia
levels when the body is under extreme duress, such as the postpartum period following childbirth, he notes.
The Phase III multi-center, randomized, double-blind, placebo-controlled, cross-over study evaluated the non-inferiority of Ravicti as compared to sodium phenylbutyrate (BUPHENYL([R])) in controlling blood ammonia
in adults aged 18 years and above with UCD.
But according to a 2005 review of 15 studies, rifaximin was at least as effective as lactulose and neomycin in improving neurologic symptoms and in reducing blood ammonia