Figure 4: Correlation between bone marrow blast cells
percentage and distinctive maturation stage of T-cell acute lymphoblastic leukemia (T-ALL) subgroups (p = 0.060).
For acute lymphoblastic leukaemia detection, features extraction plays vital role because blast cells
may have lot of information including different characteristics of their nucleus and cytoplasm .
Most of acute leukaemias can be classified as myeloid, B lymphoid and T lymphoid based on different antigenic expression of the blast cells
. However, some of the blast cells
express both lymphoid and myeloid lineage-specific antigens, so lineage assignment in this minority of cases is not possible.
The post-chemotherapy increase in peripheral blasts can be generally applied to the post-transplantation laboratory results to reflect that as a patient's new marrow (donor marrow) begins to produce white blood cells, sometimes immature or blast cells
are pushed out into the peripheral blood as well.
Plenty nucleated red blood cells and many mature and immature leucocytes including predominantly myelocytes with number of the blast cells
form 6% to 30% were present in the chronic, accelerated phases and blast crises were seen while bone marrow smear were showing hypercellularity due to excessive proliferation of myeloid cell line predominantly of myelocytes hypolobated megakaryocyts with few blue histocytes and pseudogaucher cell.
With ALL, the bone marrow releases large numbers of immature white blood cells, or blast cells
. As they increase, the number of red blood cells and platelet cells drops, causing anaemia symptoms.
CMML is a life-threatening hematologic malignancy characterized by elevated levels of monocytes, immature blood cells, or blast cells
, and abnormal cells in the peripheral blood as well as in the bone marrow.
However, the absence of blast cells
in the peripheral blood smear and the normal appearance of the liver and spleen on a subsequent abdominal ultrasound refuted a primary hematologic disorder.
PML/RAR[alpha] complexes can bind to the predicted PML/RAR[alpha] binding site in the promoter region of miR-146a, and the repressive effects of PML/RAR[alpha] complexes can be blocked by ATRA, even in primary blast cells
(2008) studying haemocytes of abalone (Haliotis sp.) had reported smaller haemocytes as "blast cells
Her peripheral blood smear showed 43% blast cells
, 42% lymphocytes, 8% monocytes, 6% neutrophils, and 1% eosinophils.
* Convertible freezers that provide four temperature zones * Six 42-pallet blast cells
"Division and differentiation of isolated CNS blast cells
Cell viability was evaluated in freshly isolated blast cells
as well as in blast cells
following incubation with chemotherapeutic drugs in 120 patients with acute leukemia (AL) using 7-amino-actinomycin D method and it was correlated with the clinical response following induction chemotherapy.
The 5 per cent and less blast cells
in sternum bone brain with its normal cells content, absence of leukaemia cells in spinal liquid were criteria of complete remission for ALL patients in our research (1,2).