On comparing the average percentage of bone marrow blast cells
in each disease subtypes, no significant differences were found and no association was noticed between the bone marrow blast cells
percentage and the three subtypes of T-ALL (p = 0.060).
For acute lymphoblastic leukaemia detection, Naive Bayes has been utilized in the recent study, where it is used to efficiently classify the normal and blast cell
from the microscopic blood images .
Characteristics FLT3 Negative FLT3 Positive Patients (n) Patients (n) 48 2 Age (years) 0-5 15 - 5-10 11 2 10-18 22 - Sex Male 26 2 Female 22 - WBC (x[10.sup.9] [L.sup.-1]) [less than or equal to] 50 38 1 >50 8 1 Unknown 2 - Hemoglobin (g [dL.sup.-1]) [less than or equal to] 10 31 - >10 16 1 Unknown 1 1 Platelet (x[10.sup.9] [L.sup.-1]) [less than or equal to] 50 21 - >50 25 1 Unknown 2 1 Blast cells
(%) [less than or equal to] 80 30 1 >80 13 - Unknown 5 1 Table 3: The frequency of translocations in the childhood AML Patients.
≥35 years), initial WBC count, blast cells
ratio in BM at diagnosis and the 15 [sup]th day of the first induction therapy, lactate dehydrogenase (LDH) at diagnosis (high vs.
The percentage of blast cells
and abnormal cells should be determined after staining with on May-Grunwald-Giemsa or a Wright-Giemsa.
Holt and Smith (1969) 17 also quoted that in acute leukemia, retinopathy has relation to high blast cell
count in circulating blood.
The phenotype of L-CFU and its correlation with the immunological characteristics of the blast cell
population in AML.
The blast cells
were suspended at a concentration of 3-5 x[10.sup.5] cells/ml in RPMI with L-glutamine without sodium bicarbonate medium (Sigma R-6504, Miami, FL).
Films were considered positive for pathologic WBCs if they showed more than 10% band forms and/or [is greater than or equal to] 1% metamyelocytes (corresponding to Left Shift), or [is greater than or equal to] 1% myelocytes and/or promyelocytes (corresponding to Immature Gran), or [is greater than or equal to] 1% blast cells
, or [is greater than or equal to] 5% atypical lymphocytes.
It operates from -50 [degrees] F to 95 [degrees] F condensing (nominal) on R-717 and R-22 for blast cell
, spiral or in-line IQF applications.
Since an early blast cell
clearance by remission induction therapy is a major independent prognostic factor, the improved outcome in our patients could be related with the initial striking decrease in leukemic cells in the bone marrow and in the extramedullary site obtained with HDMP as a differentiating- and apoptosis-inducing agent.
There is concomitant rise of lactic dehydrogenase because of rapid cell turn over in ALL.1-4 AKI may occur in ALL in absence of TLS due to renal infiltration by blast cells
, infections and volume depletion.5
"It was when they looked at the spinal fluid that they saw the leukaemia blast cells
Complete haematological remission is defined as absolute neutrophil count (ANC) 1.0 x 109/L, platelet count 100,000/ul and bone marrow blast 20% blasts, Sudan black negativity of the blast cells
and characteristic immunophenotype (for B-ALL >20% of Blast cells
express tdt, CD10, CD 19, CD 22, cCD79a and for T-ALL, cCD 3, CD 5, CD 7).
Bone marrow aspiration and biopsy were consistent with peripheral blood and demonstrated hypercellularity with about 41% blast cells