In epidermis out of 50 cases, Parakeratosis was seen in 2 cases, Hyperkeratosis in 45 cases, Acanthosis in 42 cases, Spongiosis in 40 cases, Papillomatosis in 10 cases, Saw-toothed rete ridges in 20 cases, Civatte bodies in 46 cases, Liquefactive degeneration of basal layer
in 48 cases, and Max-Joseph's space was seen in 6 cases.
atypia characterized by change in the basal cells showing pleomorphism, altered N/C ratio, prominent nucleoli, and increase in typical mitotic figures19 was reported in the present study.
Melan-A+ cells were revealed in the basal layer
of the epidermis (Fig.
As cells move up from the basal layer
they lose their capacity to divide making them fully mature cells.
Given the availability of only limited tissue, the rationale for this focused panel was representation of antibodies against both low and high molecular weight cytokeratins, as well as a transcription factor often expressed in the basal layer
of epithelia and representative mucin proteins.
On the second day after amputation, the apical epidermal cap continued well-developed (Figure 4) as well as the cells from the epithelium basal layer
(Figure 4 and 5).
The average number of melanocytes in H&E stained sections is 1 of 10 cells in the basal layer
. Because only 10 precent of the cells in the basal layer
is melanocytes, each melanocyte supplies several keratinocytes with melanin, forming with them an Epidermal- Melanin unit.
Surface-zone (of basal layer
) scales (0 = a, 1 = p)
The cystic wall was constituted by loose connective tissue covered by cuboidal basal layer
and a columnar luminal layer with interspersed scattered mucinous goblet cells confirming the diagnosis of nasolabial cyst.
Results: In the hypertrophic scar tissue, eIF6 expression was significantly decreased and absent in the basal layer
of epidermis in the early period, and increased slowly and began to appear in the basal layer
of epidermis by the scar formation time.
Among n=12 cases of dentigerous cysts, basal layer
atypia characterized by pleomorphism, altered nuclear cytoplasmic ratio and increased stratification was seen in n=6 (50%) cases.
They comprised such characteristic features as lymphohistiocytic bandlike infiltrate occupying the upper dermis and obscuring the dermoepidermal junction, irregular acanthosis resembling the typical saw-toothed appearance, extensive liquefactive degeneration of the basal layer
of the epidermis with subepidermal clefts (Max Joseph spaces), pigmentary incontinence, and numerous cytoid bodies forming huge clusters.
Fontana-Masson- stained sections show increased melanin in the compact hyperkeratotic areas and the basal layer
. Toluidine blue staining of plastic- embedded sections showed numerous keratin globules throughout the thick stratum corneum.
In sun-protected adult human skin, intraepidermal melanocytes remain in a quiescent, growth-arrested ([G.sub.0]) state within the basal layer
, proliferating approximately once a year.
The basal layer
location of UVA-induced rather than UVB-induced DNA damage, confirmed by immunohistochemical analysis, suggests that the longer wavelength ultraviolet radiation is an important carcinogen in the stem cell compartment of the skin, according to the investigators.