Experimental models of spontaneous autoimmune disease show that, at these early stages, the autoimmune response
is much more sensitive to immunointervention than in the late stages, when immunosuppression is applied to human diseases.
The company's initial offering is the Cunningham Panel(TM), a set of tests aimed at assisting clinicians in the diagnosis of PANDAS and PANS, conditions associated with motor tics, obsessive compulsive disorder (OCD), and sometimes Autism Spectrum Disorders (ASD), that researchers believe to be caused by a harmful autoimmune response
triggered by common infections.
This mutant protein supplants normal HSP70i, thereby reversing vitiligo's autoimmune response
To our knowledge, this is the first experimental animal study showing the correlation between the histopathological changes in the thyroid gland secondary to challenge with nickel and the serum autoimmune response
For them, gluten proteins trigger an autoimmune response
that can lead to serious health problems.
These antibodies promote the development of regulatory T cells and other effects to provide long-lasting control of the autoimmune response
Rather, the autoimmune response
spreads to a number of different second epitopes in these individuals, thereby exhibiting more variation than the response in patients with the early anti-Sm autoantibody response.
One theory is it's an autoimmune response
after a bladder infection, another is that there are substances in urine which irritate people with IC.
In the pathogenesis of ADEM, an initial injury caused by an infectious agent, followed by a secondary autoimmune response
, has been postulated, and animal models have provided experimental support; both CD4 and CD8 T cells have been implicated in a secondary autoimmune response
These include type 1 diabetes and celiac disease, an autoimmune response
to the cereal protein gluten.
They claim the vaccine triggers an autoimmune response
which they believe plays a role in the onset of autism.
DeCamilli thinks discoveries about SMS will go hand in hand with findings on MS observed, "We think that getting a handle on the mechanism of SMS may provide important clues about how an aggressive autoimmune response
against central nervous system antigens is mounted by the body.
MSCs were found to block the formation of scar tissue by suppressing the autoimmune response
, which would otherwise cause permanent damage to the nerves.
Research shows that IL-17A plays a role in driving the body's autoimmune response
in disorders such as moderate-to-severe plaque psoriasis and is a preferred target for investigational therapies.
But because macrophages can also be part of the autoimmune response
that damages the protective covering (myelin) of the nerves in people with MS, scientists weren't sure whether the NaV1.