Although systemic manifestations of this syndrome may include polyserositis, mental status changes, medullary fat necrosis of long bones and aseptic necrosis
of the bones were less frequently observed (1, 4, 7).
Osteonecrosis of the shoulder, also called avascular necrosis or aseptic necrosis
, was first described by Heimann and Freiberger, (1) in 1960, and by Cruess and colleagues (2) in 1968.
Steroid injections used to be fashionable but have lost favour due to the potential risks of patients developing a severe hip problem, aseptic necrosis
, as a consequence.
Intramuscular NSAIDs are known to cause aseptic necrosis
, predisposing the patient to staphylococcal abscesses.
Osteonecrosis of the Jaw (ONJ) is also known by several other names, such as avascular or aseptic necrosis
of the mandible/maxilla, bisphosphonate associated osteonecrosis of the jaw (BON), Jaw Rot, Dead Jaw disease or Bisphossy Jaw.