With this approval, Ibrance is the first and only CDK 4/6 inhibitor indicated in combination with an aromatase inhibitor
for the first-line treatment of men with HR+, HER2- metastatic breast cancer in the US.
Keywords: Anastrozole, Aromatase inhibitors
, Breast cancer, Serum estrogen level.
However, given the previously discussed data, after oophorectomy, aromatase inhibitors
are the preferred treatment option, and tamoxifen can be avoided.
Masculinization of female golden rabbitsh Siganus guttatus using an aromatase inhibitor
treatment during sex differentiation.
Key clinical point: Aromatase inhibitors
don't help shorter boys grow taller.
Use of an aromatase inhibitor
for induction of ovulation in patients with an inadequate response to clomiphene citrate.
Risk was comparable in women on aromatase inhibitors
(AIs) only and in those who used sequential tamoxifen followed by an AI, Reina Haque, Ph.D., reported at the San Antonio Breast Cancer Symposium.
This drug is non-steroidal aromatase inhibitor
; inhibitor of estrogen biosynthesis and anti-tumour agent available in market for breast cancer treatment.
She also notes that the risk reduction seen was not as much as seen with fellow aromatase inhibitor
exemestane (Aromasin) in a previous study.
We aim to determine the efficacy of bisphosphonates in preventing aromatase inhibitor
induced bone loss (AIBL) in postmenopausal women with early breast cancer.
All had been treated with an aromatase inhibitor
, a type of drug that blocks estrogen production.
In the present study, masculinization of undifferentiated yellow catfish was induced by administration of the aromatase inhibitor
(AI) letrozol (LZ).
Method: In this phase 3, randomized trial, we compared everolimus and exemestane versus exemestane and placebo (randomly assigned in a 2:1 ratio) in 724 patients with hormone-receptor-positive advanced breast cancer who had recurrence or progression while receiving previous therapy with a nonsteroidal aromatase inhibitor
in the adjuvant setting or to treat advanced disease (or both).
To circumvent this, we used hippocampal organotypic cultures treated with the aromatase inhibitor