(NASDAQ: HOOK) is a clinical stage biopharmaceutical company developing a new class of immunotherapeutics, targeting infectious diseases and cancers based on its proprietary arenavirus
platform that is designed to reprogram the body's immune system.
Hookipa Pharma is a clinical stage biopharmaceutical company developing a new class of immunotherapeutics, targeting infectious diseases and cancers based on its proprietary arenavirus
platform that is designed to reprogramme the body's immune system.
En los quiropteros frugivoros e insectivoros tambien se ha encontrado una variedad de patogenos como Dengue, virus de las encefalitis, arenavirus
, hantavirus, hepacivirus, leptospira, Bartonella, Leishmania y tripanosoma entre otros.
(2011) Pathogenesis of arenavirus
A new arenavirus
in a cluster of fatal transplant-associated diseases.
Many viruses have been identified to cause SSHL like CMV, rubella, rubeola, varicella zoster, HSV I, HSV II, parainfluenza A, B, and C, Lassa fever (Arenavirus
), EB virus, HIV with mumps virus accounting for about 7% of adult cases.
[USPRwire, Fri Oct 23 2015] Global Markets Direct's, 'Arenavirus
Infection Lassa Fever - Pipeline Review, H2 2015', provides an overview of the Arenavirus
Infection Lassa Fever's therapeutic pipeline.
 A small number of nosocomial outbreaks have occurred in SA: Marburg virus disease (MVD) in Johannesburg in 1975, CCHF near Cape Town in 1984, EVD in Johannesburg in 1996, and the Lujo virus, a newly identified arenavirus
, in Johannesburg in 2008 [7-10] (these are dealt with in detail in the 'Clinical Alert' article in this issue of SAMJ ).
Examples include the discovery of a novel arenavirus
in liver and kidney transplant tissue (2) and genome reconstruction of an epidemic strain of Shiga toxin-producing Escherichia coli found in stool samples (3).
Viral isolation studies have characterized a divergent arenavirus
associated with the disease that has envelope glycoproteins more similar to those of filoviruses than to those of other arenaviruses.
Examples in which NGS strategies have identified likely causal agents in idiopathic conditions (not all in humans) include Heartland Bunyavirus, titi monkey adenovirus, Bas-Congo virus, Theiler's disease-associated virus, Lujo arenavirus
, and many others.
Aronson, "Genistein treatment of cells inhibits arenavirus
infection," Antiviral Research, vol.
(96) Similarly, Palacios et al (97) used unbiased high-throughput sequencing to identify a previously unknown Old World arenavirus
in specimens collected from 3 recipients of visceral organ transplants from a single donor, who each died of a febrile illness.
Sometimes an arenavirus
, such as the one that causes Lassa hemorrhagic fever, will infect a human.
LCMV is an arenavirus
carried by the common house mouse.