which in the diagram contains an apocrine gland
, is shown in Figure 6.
Hidradenitis Suppurativa: disease of follicular epithelium, rather than apocrine glands
The lesions are primarily found along the "milk line," where the sites of involvement are anywhere apocrine glands
are found, including the axillae, breast, and perianal area.
Hidradenitis suppurativa (HS) is a disease characterized by chronic follicular occlusion and secondary inflammation of the apocrine glands
The disease then spreads from one apocrine gland
to another subdermally, and the patients develop subsequent abscesses in adjacent glands, causing the process to continue, Dr.
inflammation is the primary inciting event in hidradenitis suppurativa, causing follicular occlusion.
5,6) This epithelial transition mirrors the physiologic epithelial transition of the apocrine gland
to the follicular infundibulum (Figure 4).
Three types of glandular tumors like perianal or circumanal or hepatoid tumor, apocrine gland
tumor of anal sac and apocrine gland
tumor commonly occur in perianal area of canines (Parry, 2006).
adenoma and adenocarcinoma of the axilla.
DISCUSSION: Hidradenitis suppurativa is a chronic relapsing inflammatory disease originating in apocrine gland
follicles which become chronic and indolent with induration, scarring of skin appendages and sinus formation.
It originates from the apocrine glands
and is characterised by suppuration and mucopurulent secretion, fistulae, unaesthetic scars and cicatricial retractions.
9) The authors of a 2012 review noted that pilosebaceous and apocrine glands
are distributed in a pattern that overlaps broadly with locations at which EVHC have been noted and opined that such overlap is unlikely to be random.
The cells which are affected in ED are keratinocytes, leading to aberrations in development of hair, eccrine and apocrine glands
, nails, sebaceous glands, lenses and conjunctiva of the eyes, anterior pituitary gland, ears, and teeth.
However, nevus sebaceous often presents at birth with variable irregularities of morphology and distribution of sebaceous glands, but also very commonly with an absence or great reduction in the number of mature hair follicles and, in the presence of ectopic apocrine glands
, features not seen in SESD (17).
are located most prominently in the armpits.