Antimicrosomal and antithyroglobulin antibodies
were measured in 37 cases (22 controls and 15 SHypo).
Thyroid antiperoxidase antibodies (TPOAbs) and antithyroglobulin antibodies
are demonstrated in the sera of 90% of patients with HT.
The superiority of antimicrosomal over antithyroglobulin antibodies
for detecting Hashimoto's thyroiditis.
Thyroglobulin (TG) might be produced in small amounts by the orbital fat tissue, so antithyroglobulin antibodies
(TGAb) seem to be of practical interest in GO (9-12).
Serum cortisol and urine 17-hydroxycorticosteroid, 17-ketosteroid, and titers of serum antithyroglobulin antibodies
and antibodies to thyroid peroxidase were also normal.
Both were from iodine-sufficient areas and tested positive for antithyroid peroxidase antibodies and negative for antithyroglobulin antibodies
07ng/ml (0-8-2) Antimicrosomal antibodies (AMA/anti TPO) >600 IU/ml (<34) Antithyroglobulin antibodies
One year earlier, the same authors reported a somewhat higher incidence of thyroid disease in a larger series (n=104) of MG patients (6% with thyrotoxicosis, 2% with hypothyroidism, 12% had antithyroglobulin antibodies
and 28% had antimicrosomal antibodies) (6).