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The patient was negative for hepatitis A, B, and C virus antibodies and antimitochondrial antibodies and had a negative direct Coombs test result.
During follow-up, all autoimmune serologic tests--including tests for anti-smooth-muscle antibodies, antimitochondrial antibodies, gastric parietal cell antibodies, rheumatoid factor, anti-Rho, anti-La, SS-A, SS-B, RNP, and antinuclear antibodies--were negative.
Protein electrophoresis, antistreptoly-sin-O-titer, complement C3 and C4, circulating immune complexes, antinuclear antibodies, p- and c-antineutro-phil-cytoplasmic antibodies, antimitochondrial antibodies, and antiacetylcholine-receptor antibodies were negative and/or normal.
Antimitochondrial antibodies, normally found in about 95% of patients with PBC, were found in 84 of the PBC patients.