The antimicrobial spectrum
of reuterin includes both Gram-positive and Gram-negative bacteria.
These include better tissue penetration, broader antimicrobial spectrum
, and fewer gastrointestinal side effects.
of bacteriocin-like substances produced by rumen staphylococci.
Although the initial cost of treatment with an amino-glycoside or a sulfonamide might be lower, the clinician must keep in mind that their limited antimicrobial spectrum
might require the subsequent use of additional parenteral antibiotics or the prolonged use of topical therapy, which then increases the overall cost of treatment.
Delafloxacin is a unique hospital antibiotic that offers both IV and oral versatility with a broad antimicrobial spectrum
in areas where today's antibiotics are not fully effective including: methicillin resistant Staphylococcus aureus (MRSA), quinolone-resistant Gram-positives, Gram-negatives and anerobes.
vice president of clinical affairs at Cempra Pharmaceuticals, described the potential utility of solithromycin as a bio-defense agent due to its broad antimicrobial spectrum
, safety and tolerability, once-daily dosing, high tissue penetration, intracellular accumulation, and compound stability.
The drug has therapeutic advantages over first-line antibiotics such as erythromycin and amoxicillin, including better tissue penetration, broader antimicrobial spectrum
, and fewer gastrointestinal side effects, Ms.