"We urgently need new classes of antifungal agents
for Candida vaginitis," he said.
Luliconazole is one of the most potent and broad- spectrum topical antifungal agents
in development and will be advancing to Phase 3 clinical development in the U.S.
Caspofungi: an echinocandin antifungal agent
. Clin Ther 2002;24:351-377.
MYCAMINE is a member of a new class of antifungal agents
, the echinocandins.
AmBisome is the only antifungal agent
indicated for the treatment of febrile neutropenia with suspected mycotic infection.
The patients in the study, which was funded by Medicis, followed the avoidance regimen and applied the broad-spectrum antifungal agent
ciclopirox 0.77% lotion twice a day for 6-12 weeks.
His discoveries have led to the development of a new anti-inflammatory drug by Pharmacia and a unique antifungal agent
for grain crop protection by Monsanto.
Even the KOH study can be misleading, however, if a patient recently self-administered a topical antifungal agent
. This article describes the varying appearance of tinea infections according to their anatomic location, and outlines a careful work-up.
Another line of evidence centered on an experimental antifungal agent
called leptomycin B.
consumer health care unit and McNeil Consumer Products Co., a subsidiary of Johnson & Johnson (J&J), completed a trade in which the former acquired Nasalcrom and Pediacare, a line of children's cough/ cold medications, from McNeil and Micatin, an antifungal agent
, from J&J.
SCY-078, an investigational antifungal agent
that is a semi-synthetic derivative of the natural product enfumafungin, is in clinical development for the treatment of several serious fungal infections, including invasive candidiasis, invasive aspergillosis, refractory invasive fungal infections, and vulvovaginal candidiasis.
announced today that Sato Pharma and Eisai will co-promote a new triazole class oral antifungal agent
(development code: BFE1224, "the agent") containing the active ingredient fosravuconazole L-lysine ethanolate ("fosravuconazole") in Japan, based on an agreement between the three companies.
The product is an orally available antifungal agent
that inhibits a metalloenzyme target named fungal CYP51.
WAIKOLOA, HAWAII -- The familiar oral triazole antifungal agent
itraconazole is under active investigation for an unexpected use: as adjunctive therapy in patients with locally advanced or metastatic basal cell carcinoma.
Other than timing of antifungal therapy, the adequacy of antifungal agent
used has been shown to have a significant impact on treatment efficacy.