Hormone receptor expression in invasive breast cancer among Korean women and comparison of 3 antiestrogen
receptor antibodies: a multi-institutional retrospective study using tissue microarrays.
Potential significance of antiestrogen
therapy in the development of bisphosphonate related osteonecrosis of the jaw.
Our work, as well as that of others (8, 9, 11, 12), would predict that second-line AIs would not help, whereas an antiestrogen
The pure antiestrogen
ICI 182,780 (7-[9-[4,4,5,5,5-pentafluoropentyl) sulfinyl [nonyl]-estra-1,3,5(10)-triene-3,17diol) and 17[beta]-3-benzoate (E2B) (Estr-1, 3,5 (10)trien-3, 16[alpha], 17[beta]-triol) were obtained from Sigma-Aldrich (Hamburg, Germany).
Synergistic Effect: The majority of data evaluating synergism between antiestrogen
therapies and natural agents are from animal or cell studies, but they do suggest potential.
Morphological changes induced by 6-month treatment of intact and ovariectomized mice with tamoxifen and the pure antiestrogen
Basic guide to the mechanisms of antiestrogen
Induction of ovulation by clomiphene citrate in PCOS is another common option of treatment for PCOS but this use is restricted only to ovulation induction as clomiphene basically being an antiestrogen
has nothing to do with the pathology of PCOS and it does not address the underlying abnormalities of PCOS including hyperinsulinemia and hyperandrogenism (Guzick 2007).
Tamoxifen is a synthetic nonsteroid triphenyl antiestrogen
drug, structurally similar to the ethylstibestriol.
ER status is significant because it strongly predicts the efficacy of antiestrogen
therapies such as tamoxifen and aromatase inhibitors.
tamoxifen significantly decreased the luciferase activity at concentration of 500 nM (P<0.
The sections were incubated overnight at 4[degrees]C with the following primary antibodies: anti-Androgen receptor (clone AR441, 1/50 dilution, Dako, Carpinteria, CA, USA), antiEstrogen
receptor (clone 1D5, 1/50 dilution, Dako, Carpinteria, CA, USA) and anti-Progesterone receptor (clone PgR 636, 1/50 dilution, Dako, Carpinteria, CA, USA).
If your tumor expresses estrogen, then you are a candidate for the antiestrogen
They cited research indicating that half of breast cancer patients who experience hot flushes while on antiestrogen
medication become noncompliant with the regimen after 180 days.
Hot flashes and sleep dysfunction are common in breast cancer survivors, particularly those who use antiestrogen