This sub-analysis evaluates the efficacy and safety of perampanel by baseline antiepileptic drugs
in subjects 12 years of age or older with uncontrolled PGTCS and taking 1-3 concomitant antiepileptic drugs
Fycompa is an antiepileptic drug
that reduces neuronal hyperexcitation associated with seizures by targeting glutamate activity at postsynaptic AMPA receptors.
Mothers who had epilepsy provided data about the use of antiepileptic drugs
during pregnancy and breastfeeding.
It also has minimal effects on the disposition of other antiepileptic drugs
and can be used synergistically, making it an ideal adjuvant medication for patients with refractory epilepsy.
Since women in the study were taking antiepileptic drugs
throughout pregnancy, it is unclear whether the effects on IQ are related to the timing or duration of prenatal valproate exposure, so "exposure to valproate at any time during pregnancy should be considered to have the potential to result in decreased IQ in children," the advisory says.
These trials were conducted in patients with uncontrolled partial onset seizures despite taking one or two antiepileptic drugs
, and included patients taking Keppra=AE.
However, antiepileptic drug
treatment of a first seizure should take into account the risk of seizure recurrence and the risk of acute and chronic adverse effects of the medication.
6 months, 50 were seizure free at 3 months, and 49 of those children were treated with antiepileptic drugs
In a multivariate analysis of the intent-to-treat sample of 310 children, IQ was lower among children exposed in utero to valproate compared with children of mothers who took other antiepileptic drugs
(AEDs) during pregnancy.
Based upon the 1,855 questionnaires returned, 51% of respondents claimed they did not receive any advice about possible drug interactions between antiepileptic drug
therapy and contraceptives.
SAN ANTONIO -- If at first you don't succeed, try, try, and even try again when it comes to finding an effective antiepileptic drug
for your treatment-resistant patients, said Dr.
Because epilepsy is one of the most common neurologic disorders, neuroscience nurses need to be knowledgeable of new developments in antiepileptic drug
TORONTO -- A standard dose of the antiepileptic drug
carbamazepine allowed ovulation and the potential for pregnancy in women using low-dose birth control pills in a small randomized, double-blind study of healthy women without epilepsy.
Levetiracetam (LEV) was identified as a commonly used concomitant antiepileptic drug
in two Phase III studies.
Klitgaard to be Honored at Antiepileptic Drug
and Device Trials XII Conference in Miami May 15-17