The findings highlight the importance of future studies on the risk-benefit ratio of antiepileptic drugs
in old adults and especially in those with Alzheimer's disease.
"Although several antiepileptic drugs
have been associated with Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), the class effect and impact of other AEDs are not well described," Eric P.
ISLAMABAD:People using antiepileptic drugs
are at a greater risk of Alzheimer's disease and dementia, finds a study.
All patients of either gender aged below 18 years, diagnosed with epilepsy and with no change in antiepileptic drug
therapy in the last 3 months, attending the outpatient Departments of Medicine, Neurology, inpatients of medical wards, or those presenting to the emergency room of a tertiary care hospital were not recruited.
Effects of long term antiepileptic drug
monotherapy on vascular risk factors and atherosclerosis.
Herzog and his associates examined the frequencies of seizure outcomes on hormonal and nonhormonal contraceptives stratifying by type of antiepileptic drug
women used when starting a particular contraceptive method.
Fycompa is an antiepileptic drug
that reduces neuronal hyperexcitation associated with seizures by targeting glutamate activity at postsynaptic AMPA receptors.
Mothers who had epilepsy provided data about the use of antiepileptic drugs
during pregnancy and breastfeeding.
Adverse reactions to antiepileptic drugs
(AEDs) occur to a certain degree in almost 80% of patients and are a major concern for physicians (1, 2).
Patients in the study who withdrew from antiepileptic drug
(AED) treatment were not significantly more likely to have seizure recurrence than were those who did not, thereby meeting the common secondary goal of discontinuing or reducing AEDs after epilepsy surgery Thus, the findings of this study may provide reassurance to neurologists who are hesitant to withdraw AEDs after surgery because of concerns that seizures may recur, Dr.
Other important variables evaluated by the investigators include maternal epilepsy, use of other antiepileptic drugs
, and antiepileptic drug
(SeeNews) - Dec 4, 2012 - Belgian biopharmaceuticals company UCB SA (EBR:UCB) today presented new data aimed at increasing understanding of short- and long-term clinical profile of antiepileptic drug
 Nettekoven S, Strohle A, Trunz B, Wolters M, Hoffmann S, Horn R, Steinert M, Brabant G, Lichtinghagen R, Welkoborsky HJ, Tuxhorn I, Hahn A, Effects of antiepileptic drug
therapy on vitamin D status and biochemical markers of bone turnover in children with epilepsy, Eur J Pediatr, 2008; 167(12)0369-1377.
Phase III clinical trials of UCB's antiepileptic drug
(AED) in development, brivaracetam, are underway, as adjunctive therapy in patients with refractory partial-onset epilepsy.
Of the participants, 29 percent were taking a selective serotonin reuptake inhibitor, commonly used for depression, and 17 percent were taking an antiepileptic drug
, usually to help control pain.