such as gabapentine and pregabalin showed good efficacy (9).
In the centuries prior to 1882 when the first synthetic anticonvulsant drug
, paraldehyde, became available, the people of central Europe depended mainly on plants to treat epileptic seizures.
The company said it has filed its abbreviated new drug application (ANDA) for the generic version of Lamictal XR (lamotrigine extended-release tablets), an anticonvulsant drug
used in the treatment of epilepsy.
The anticonvulsant drug
pregabalin was the only treatment that had strong evidence in support of its effectiveness (Neurology DOI 10.1212/WNL.0b013e3182166e be).
Out of all patients of exfoliative dermatitis, 4 (66.7%) had taken indigenous drug, 1 (16.7%) had anticonvulsant drug
and 1 (16.7%) had quinolone intake history (Table 4).
He explained that following this and other experiments, a drop of broad bean concentrate was examined by a form of chemical analysis (chromatography) and compared with drops of phenobarbitone (anticonvulsant drug
), valium and glycine substance.
Your doctor gave you a prescription for an anticonvulsant drug
to treat your migraine headaches and one day you noticed you had lost some of your muscle strength.
Although most of the drugs had no effect or were toxic to the worms, Kornfeld's team found that ethosuximide, an anticonvulsant drug
, increased the worms' life span by 17 percent.
Studies of patients taking this anticonvulsant drug
suggest that bacterial plaque is an important determinant of the severity of phenytoin-induced gingival overgrowth and stress the importance of instituting preventive plaque control programs, principally in young patients taking this drug.
In some of experimental studies in animals, the anticonvulsant drug
phenytoin were administered in embriotoxic daily doses (100-1500 mg Kg-1 bd.wt.) increasing concentrations up to 20 times the human therapeutic plasma concentration.
At lower doses (20-50 mg/kg, i.p) the alkaloid proved to be effective in inhibiting pentylenotetrazol- (PTZ 100 mg/kg, s.c) and maximal electroshock-induced seizures (80 mA, 50 pulses/s, 0.2 s), suggesting its potential as an anticonvulsant drug
. However, at higher doses ([greater than or equal to] 75 mg/kg, i.p) a convulsant activity was observed.
Gabapentin is a novel anticonvulsant drug
that was introduced in the early 1990s and later approved (1995) for use in the US as an adjunctive treatment of partial seizures with or without secondary generalization in persons >3 years of age.
Recently, for example, a new anticonvulsant drug
called gabapentin has come on the market.
somnifera (Dunal) (Ashwagandha) extract provide a promising anticonvulsant drug
having higher efficacy against absence (petit mal seizures and moderate efficacy in generalized tonic-clonic (grand mal) seizures with no or acceptable adverse effect like mild sedation, more work is needed to isolate the active principle and to further evaluate it to that availability of such drug becomes a reality.