While it is the standard of care to avoid using anticholinergic drugs
in the elderly, it is precisely this age group that is most likely to suffer from the conditions these drugs treat--for example, problems with bladder control, depression, and poor sleep.
After 12 months, the rate of anticholinergic drug
use fell to a high of 11% on haloperidol and 6% for amisulpride.
Synthesis of the optical isomers of a new anticholinergic drug
, penehyclidine hydrochloride (8018).
Two new anticholinergic drugs
, solifenacin and darifenacin, were released in 2004, followed by fesoterodine in 2008 (Ellsworth & Kirshenbaum, 2010).
Withdrawing anticholinergic drugs
from patients taking them promises to reduce symptoms of MCI, but is unlikely to reduce rates of Alzheimer's (SOR: C, well-designed observational study).
He supported the continued use of an anticholinergic drug
in selected patients with COPD despite results from two studies reported last September that called into question the safety of this drug class in patients with COPD.
If it is severe and affects the scalp as well, medication can help, such as the anticholinergic drug
If you have generalised sweating, your doctor may prescribe an anticholinergic drug
In the present study, we tested the effects of the anticholinergic drug
, oxitropium bromide (OTB), on lung function, exercise capacity, and exertional dyspnoea in elderly COPD patients (more than 75 years old) using a double-blind placebo-controlled study, in comparison with middle-aged patients (less than 65 years of age).
Australian William McBride, founder and director of Foundation 41, a private research organization, faces allegations of fraud regarding research on the anticholinergic drug
Patients under 20 years of age using a prescription for an anticholinergic drug
for the first time ever between April 2007 and March 2008 were identified using IMS Brogan's Public and Private Drug Plans database.
Taking one moderately anticholinergic drug
simulated an extra three to four years of age.
With rare exceptions, an anticholinergic drug
should not be added to an atypical antipsychotic--it's likely to increase negative symptoms and cognitive dysfunction, and magnify the risk of tardive dyskinesia.
Those who took at least 10 milligrams (mg) per day of the tricyclic antidepressant doxepin (Sinequan[R]), 4 mg per day of the antihistamine diphenhydramine (Benadryl[R]), or 5 mg per day of the anticholinergic drug
oxybutynin (Ditropan[R]) for more than three years were found to be at greater risk for dementia.
Anticholinergic medications can worsen bladder-emptying problems and increase the risk of urinary retention in men with urge incontinence and BPH, so your physician should treat your BPH before prescribing an anticholinergic drug