The evidence regarding the antibody is not conclusive; even if correct, the stability in this particular antibody-antigen complex
may be an idiosyncratic characteristic rather than a general one.
When incubated with a sample, the antibody-coated beads bind to cell surface antigens forming an antibody-antigen complex
between the beads and the target molecules.
Hobart, Australia) have patented a predictive test for rheumatoid arthritis comprises the detection of antibodies to collagen in a biological sample from a patient by contacting the biological sample with an antigen comprising the CB10 peptide of mammalian type II collagen, or an antibody-binding fragment or variant thereof, for a time and under conditions for an antibody-antigen complex
to form, and detecting the antibody-antigen complex
, for example by immunoassay.
In immunodetection amplified by T7 RNA polymerase, a double-stranded oligonucleotide containing the T7 promoter is conjugated to an antibody, and then T7 RNA polymerase is used to amplify RNA from the double-stranded oligonucleotides coupled to the antibody in the antibody-antigen complex
When mixed with a sample suspension and incubated, the antibody-coated beads bind to cell surface antigens forming an antibody-antigen complex
with the target molecules.