Furthermore, the patients treated with Class IA antiarrhythmic drugs
were more likely to have an ES.
Continued treatment with an antiarrhythmic drug
in the drug-arm patients, compared with no drug treatment in the ablated patients, "is absolutely the explanation" for the observed difference in quality of life, she said.
Previous randomised trials have reported that pulmonary vein isolation is more effective in preventing atrial fibrillation (AF) than antiarrhythmic drugs
Brinavess is an antiarrhythmic drug
that acts preferentially in the atria by prolonging atrial refractoriness and slowing impulse conduction in a rate-dependent fashion.
Health outcomes with catheter ablation or antiarrhythmic drug
therapy in atrial fibrillation: Results of a propensity-matched analysis.
Brugada syndrome is diagnosed in patients with ST-segment elevation with type I morphology [greater than or equal to]2 mm in [greater than or equal to] 1 lead among the right precordial leads V1,V2 positioned in the 2nd, 3rd, or 4th intercostal space occurring either spontaneously or after provocative drug test with intravenous administration of Class I antiarrhythmic drugs
In a meta-analysis of prospective studies published through 2007, the single-procedure success rate for radiofrequency ablation in achieving sinus rhythm without the use of antiarrhythmic drugs
was 57%, climbing to 71% with multiple ablation procedures.
Two potential antiarrhythmic drugs
are in late-stage development and are forecast to enter the market within the next decade: Gilead's ranolazine/dronedarone and ChanRx's vanoxerine.
DISCUSSION: Amiodarone is an iodine containing highly lipophilic class III antiarrhythmic drug
used in ventricular and supraventricular arrhythmias.
This option may be considered for paroxysmal AF in patients who are refractory or intolerant to antiarrhythmic drugs
We are in absolutely agreement with authors about the improving effects of antiarrhythmic drug
therapy on prognosis in AF.
Multiple ectopic beats that are causing palpitations, or that occur after a myocardial infarction, can be treated with an antiarrhythmic drug
In a consensus statement published in April, the Heart Rhythm Society and other organizations recommended ablation for symptomatic paroxysmal Afib that has not responded to at least one antiarrhythmic drug
, but they also noted that the procedure is "reasonable" as a first-line treatment for this type of Afib or for symptomatic persistent Afib that has failed medical therapy.
For patients with low risk, dronedarone provides the only antiarrhythmic drug
with a large safety database to prove reasonable safety," he added.
Amiodarone, an antiarrhythmic drug
approved for controlling life-threatening recurrent ventricular arrhythmias, is marketed as Cordarone and Pacerone.